The second thing that we learned is that we were not able to show an impact on time to disease progression in the way that we measured it, which was the time to the next progression event or two lesions in the bone.

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It seems to be occurring more frequently in the 1580 leads, particularly in the 8 French, and that with time we are going to see progression.

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It was left to a more experienced head to make Chelsea's progression to the quarter-finals secure, as Deco was given time and space in the box to collect Cole's left-wing cross, control and fire in to the bottom right-hand corner of Al Habsi's net.

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The study was designed to measure progression-free survival, which is a measurement of the time from the start of treatment until the disease gets worse or the patient dies, and overall survival, which is a measurement of time from the start of treatment until death.

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In a tougher measure of efficacy that takes into account how long patients lived, called progression-free survival, Thalomid more than doubled the length of time patients lived, to 57 weeks.

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"It's a frightening and exhilarating thing to do for the first time, " he said, adding that going into cinema seemed a natural progression for him.

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