But there is reason to doubt that Sanofi's success with Acomplia will come from obesity alone.
One reason to doubt her spying credentials is that Ms Zatuliveter was so conspicuous.
You know how high expectations can be and how setbacks can cause people to doubt.
Yet there were always reasons to doubt that a genuine policy shift was under way.
Whether all this really leaves America with no alternative to unilateralism may be open to doubt.
Now, of course, those marketing geniuses at MicroProse have cause to doubt their wisdom.
Possibly, though there are reasons to doubt that would be willing to do even that.
But following his pledge to talk to such groups, America seems to doubt his commitment.
Nevertheless, it would be difficult to doubt his 50-year obsession with his dead mother.
There are just as many reasons to doubt that such an election would be feasible, however.
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But she says she began to doubt herself when she felt undermined by a manager.
Whether these sanctions will bite is open to doubt given the difficulty of policing jobs.
Whether intractable social problems can be solved quite so magically is open to doubt.
They all insist there's no problem - and so far, there's no reason to doubt them.
The skeptics happily took your commentary last year as reason to doubt our results!
Whether it will succeed in becoming a true multi-utility, though, is still open to doubt.
But repeated disappointments have led some experts to doubt whether antisense makes any sense at all.
Looking at its origins, the best we can do is say the question is open to doubt.
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Skeptics have plenty of grounds to doubt whether the new test really takes us any further forwards.
Yet stand by the sea and watch the irregularity of its edge, and you begin to doubt.
There are a few other reasons to doubt the sustainability of the rally of the last seven days.
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"There is no reason to doubt the fall in suicide in England in the last decade, " he added.
At this point there is little reason to doubt Iran's responsibility for the plot against the Saudi Ambassador.
Will we start to doubt the news stream and thus have a more serious lag in how we respond?
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Nevertheless, a heterosexual boy is likely to doubt himself, wondering why he was chosen by a man for sex.
Better for the stock price to quiet the critics who had one more reason to doubt the numbers.
The second reason to doubt Republican tactics is the cleverness of President Clinton.
But some ask whether political independence could lead to doubt as to how far London would back Scotland financially.
What is more, there are reasons to doubt that mass imprisonment can take the lion's share of the credit.
Even this scenario of modest change and modest improvement is subject to doubt.
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