This can turn a non-toxic substance called 5-fluorocytosine into a nasty chemical called 5-fluorouracil that kills all cells, normal and malignant.

ECONOMIST: Cancer treatment

The American Medical Association, the American Public Health Association and the American Nurses Association have previously called for changes in the Toxic Substance Control Act.

CNN: Pediatricians urge tougher chemical safety law

Where companies need to be careful in dealing with both compliance and innovation, Kirschner cautions, is when substituting a known toxic substance with an alternative.

FORBES: How International Regulations Are Changing American Supply Chains

The toxic substance quickly moves its way up the food chain.

CNN: Tomorrow Today

In California, the Department of Toxic Substance Control brought charges against a geothermal plant for improper disposal of cartridge filters used to remove inorganic solids from the return water.

FORBES: Google Funded Project Confirms Vast Potential for Geothermal Energy

The Office for State, Tribal, Local and Territorial Support (OSTLTS) serves as the primary link between the Centers for Disease Control and Prevention (CDC), the Agency for Toxic Substance and Disease Registry (ATSDR), and Tribal governments.

WHITEHOUSE: Resources within U.S. Federal Agencies | The White House

Although DDT is a (modestly) toxic substance, there is a world of difference between applying large amounts of it in the environment--as farmers did before it was banned--and applying it carefully and sparingly to fight mosquitoes and other disease-carrying insects.

FORBES: Beyond Copenhagen

In addition to any potentially toxic effects, fragrance is routinely listed as a substance to avoid as a potential allergen, for both adults and babies.

FORBES: File Under Ridiculous: Perfume for Babies

Overuse of vitamin D, a substance that promotes the growth of bone and teeth in children, can be particularly toxic, as can overuse of the mineral iron by older adults.

CNN: ASIANOW - TIME Asia