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The top quarter of the draw has a surprising look following the early exit of top seed Roger Federer, with his conqueror Ernests Gulbis beating Filippo Volandri 6-2 3-6 7-6 (7-4) to set up a clash with Feliciano Lopez, who had a walkover after Ivan Ljubicic pulled out with a back injury.
BBC: Andy Murray loses to David Ferrer at Rome Masters
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In the other half of the draw, second seed Svetlana Kuznetsova received a walkover when unseeded Spaniard Anabel Medina Garrigues pulled out with a back injury.
CNN: STORY HIGHLIGHTS
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World number two Rafael Nadal , who Murray is seeded to meet in the semi-finals, was given a walkover into the next round when his opponent Olivier Rochus pulled out with a foot injury.
BBC: SPORT | Tennis | Effortless Murray beats Kendrick
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It is the second walkover of the week for fourth-ranked ranked Murray, whose third round opponent Milos Raonic of Canada also pulled out through injury.
CNN: Djokovic to face Murray in Miami final