Giovanni van Bronckhorst, Wesley Sneijder and Arjen Robben each scored to earn a clash with Spain or Germany.
Only in the closing minutes did Inter threaten with Maicon, striking substitute Samuel Eto'o and Wesley Sneijder going close.
CNN: Inter held by Genoa in San Siro but stay four points clear
Fellow Dutch internationals Ruud van Nistelrooy, Arjen Robben and Wesley Sneijder have all been linked with moves away from the Bernabeu.
In Serie A, Sulley Muntari and Wesley Sneijder were on target as champions Inter Milan beat Catania 2-1 to stay top.
CNN: Real Madrid held goalless in Spain; Inter stay top in Serie A
Brazilian goalkeeper Julio Cesar hoisted a long kick forward and Milito held off Martin Demichelis to work it back to Wesley Sneijder.
CNN: Milito double as Inter Milan crowned champions of Europe
In other friendly action on Saturday, the Netherlands beat Japan 3-0 in Enschede with Robin van Persie, Wesley Sneijder and Klaas-Jan Huntelaar on target.
Robinho had given Brazil the lead only for the Dutch to draw level through a Felipe Melo own goal before Wesley Sneijder's 68th-minute headed winner.
Wesley Sneijder restored the Dutch side's lead despite Robin van Persie appearing to be offside, and an Arjen Robben header made it 3-1 three minutes later.
But Galatasaray, boasting the likes of Didier Drogba and Wesley Sneijder, was soon level thanks to a stunning 25-yard drive from former Schalke player Hamit Altintop.
In one of the few moments of note early on, Wesley Sneijder stung the palms of Neuer with a drive that was directed straight at the goalkeeper.
The young centre-back, making his first Champions League start, found himself unmarked from Wesley Sneijder's free-kick but he turned his effort wide from a few yards out.
Elsewhere, Galatasaray fielded both major January signings -- Wesley Sneijder and Didier Drogba -- in their home clash with Germans Schalke but were held to a disappointing 1-1 draw.
Forlan polled 23.4 percent of votes cast by journalists covering the World Cup, to finish ahead of Dutch playmaker Wesley Sneijder (21.8 percent) and Spain striker David Villa (16.9%).
But there were also a few moments of real quality, none more so than a sumptuous through ball from the largely anonymous Wesley Sneijder that played Robben clean through on goal.
Both have spent massively, PSG approaching half a billion dollars in two years, Galatasaray substantially less, but still enough to attract two highly paid veteran reinforcements in January: Wesley Sneijder and Didier Drogba.
Dutch international trio Klaas-Jan Huntelaar, who has been linked with Tottenham Hotspur, Rafael van der Vaart and Wesley Sneijder are all thought to be for sale to offset some of the massive spending.
But Jose Mourinho's men were down to 10-men just after the hour as midfielder Wesley Sneijder went for two bookable offences and Atalanta capitalized with an equalizer by substitute Simone Tiribocchi on 81 minutes.
Two goals in three second-half minutes by Wesley Sneijder and Arjen Robben helped to see off a resolute Uruguay side and put the Netherlands into a World Cup final for the first time since 1978.
Wesley Sneijder's powerful 52nd-minute winner from just outside the box settled a fascinating Group E contest between two contrasting sides who opened up in the second half and were creating good chances right up to the final whistle.
Dutch midfielder Wesley Sneijder may miss the match after injuring an ankle in training on Monday, while goalkeeper Julio Cesar and center-back Ivan Cordoba also face late fitness tests after picking up knocks in Saturday's 3-0 win over Bologna.
Goran Pandev's 22nd-minute strike from long range failed to dip quickly enough to prevent it going over while Wesley Sneijder could only shoot harmlessly wide in the final minute of the half after a neat one-two with fellow attacker Milito.
With the ball won just inside the Chelsea half, firstly Thiago Motta and then Samuel Eto'o fed the ball through for Milito who, with space afforded by Wesley Sneijder's presence, stepped inside John Terry and beat Petr Cech at the near post.
Spanish giants Real are seeking to balance the books after a summer of massive spending and are set to offload other members of their Dutch contingent, with Wesley Sneijder, Rafael van der Vaart, Ruud van Nistelrooy and Arjen Robben all the subject of transfer speculation.
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