In clinical trials, Cincinnati's Nasrallah notes, Vietnam veterans did not respond to Zoloft and Paxil.
Zoloft, the antidepressant, and Norvasc, its big-selling hypertension drug, were the culprits in the second quarter.
Plumlee, who watched the "60 Minutes" program, saw it as proof she'd been right about Zoloft.
Now, it is losing market share rapidly to competitors such as Pfizer's Zoloft and SmithKline Beecham's Paxil.
Her doctors tried everything from Zoloft to mood stabilizers to heavy-duty antipsychotics, but none of them helped for long.
Not so, according to plaintiff Laura A. Plumlee, who says Zoloft didn't help her during three years of treatment.
New data have forced antidepressants, like Paxil and Zoloft, to carry warnings that they may cause suicidal thoughts in adolescents.
But it is facing similar problems, as big-selling drugs like Zoloft, for depression, and Norvasc, for hypertension, lose patent protection.
Several blockbuster drugs lost patent protection in 2006, such as the statin Zocor from Merck and the antidepressant Zoloft from Pfizer.
Stanford has been taking the anti-anxiety and depression drugs Klonopin, Remeron and Zoloft, according to testimony cited in the court order.
FORBES: Jailed Billionaire Stanford: Drug Addicted, Delirious, Possibly Brain Damaged
Plumlee, 49, said in an exclusive interview that she took Zoloft from 2005 through 2008, while her doctor repeatedly increased the dose.
It asks the judge to order Pfizer to correct "misleading" information in Zoloft's package insert and refund everything California patients paid for Zoloft.
These drugs, which include Zoloft, Prozac, and others, are widely considered to be the safest type of antidepressant medication to take during pregnancy.
Pfizer has bombarded doctors with pamphlets claiming that Zoloft works just as well as Prozac for a broader range of symptoms, with fewer side-effects.
Your doctor may prescribe one of several selective serotonin reuptake inhibitors (SSRIs), such as sertraline (Zoloft), paroxetine (Paxil) or fluoxetine (Prozac), to help delay ejaculation.
The case also is unusual because Zoloft has had cheap generic competition since 2006, so it's no longer advertised, and little brand-name Zoloft is sold.
Prozac and its various descendents are a huge presence on our most-popular list, with Lexapro, Zoloft (No. 7), Cymbalta (No. 8) and Effexor (No. 10) all making appearances.
The biggest controversy is whether Pfizer will spin off its established products unit, which sells generic drugs and branded medicines like Norvasc and Zoloft that have lost patent protection.
So-called selective serotonin reuptake inhibitors such as Paxil, Prozac and Zoloft, gained widespread use on the theory that depressed people suffer from a deficit of the brain chemical serotonin.
As with other compulsive behaviors like gambling and drinking, Delmonico recommends therapy and 12-step programs, although antidepressants (drugs llike Paxil or Zoloft) and antipsychotics like (these include Abilify and Zyprexa) may help.
The suit accuses Pfizer of consumer fraud and other offenses, including quietly paying prominent doctors to tout Zoloft to colleagues or to be listed as authors of positive medical journal articles the company prepared for publication.
For proof, one need only ask how many psychiatrists practice their trade in Pakistan or Bangladesh, or how many citizens of both countries avail themselves of the various anti-depressants marketed by pharmaceutical concerns, including Prozac, Zoloft and Paxil.
Brent Wisner of the Los Angeles firm Baum Hedlund Aristei Goldman, argues the Food and Drug Administration shouldn't have approved Zoloft because Pfizer didn't publish some clinical studies that found the drug about as effective as a placebo.
It's gone so mainstream that even huge health plans, like UnitedHealth Group, are encouraging their members to split pills--offering members free splitter devices. (Check out halftablet.com) The company says 21 common medicines--including Crestor, Lipitor, Lexapro and Zoloft, are ripe for splitting.
UnitedHealth Group ( UNH - news - people ), are encouraging their members to split pills--offering members free splitter devices. (Check out halftablet.com) The company says 21 common medicines--including Crestor, Lipitor, Lexapro and Zoloft, are ripe for splitting.
应用推荐