本发明可在简单的极性有机相模式下拆分佐米曲坦和拉米夫定等药物对映体。
The present invention may be used in simple polar organic phase mode to resolve the medicine antimer of zolmitriptan, lamivudine, etc.
曲坦类化合物是一类重要的治疗偏头痛的药物，现已开发出来的有舒马曲坦，纳拉曲坦、 佐米曲坦、 利扎曲坦、阿莫曲坦、依利曲坦和氟伐曲坦。
Triptans is a kind of important drug for migraine. So far, sumatriptan, nalatriptan, zlmitriptan, zizatriptan, almotritan, eletriptan and frovatriptan have appeared on the market.
目的建立手性分离方法并检查佐米曲普坦光学纯度。
Objective To establish method for chiral separation and inspect the purity of Zolmitriptan.
前言： 目的：改进佐米曲普坦的合成工艺。
Objective: To improve the synthesis technology of zolmitriptan.
结果：改进了佐米曲普坦的合成工艺，总收率提高至16%。
Results: We successfully improved the synthesis technology of zolmitriptan with an overall yield of 16%.
结果：改进了佐米曲普坦的合成工艺，总收率提高至16%。
Results: We successfully improved the synthesis technology of zolmitriptan with an overall yield of 16%.
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