凋亡诱导因子,小鼠,对照肽(aif)。
结果细胞因子、辐射、氧自由基等可诱导血管内皮细胞凋亡,导致血管损伤;
Results Cytokine, radiation could induce apoptosis of endothelial cells, and caused vascular damage.
目的探讨肿瘤细胞表面dr5表达水平与其对肿瘤坏死因子相关的凋亡诱导配体(TRAIL)敏感性之间的关系。
Objective to investigate the correlation between sensitivity to tumor necrosis factor-related apoptosis inducing ligand (TRAIL) and expression level of death receptor 5 (DR5) on tumor cell surface.
流感病毒诱导的细胞凋亡,涉及到各方面的问题,包括细胞和病毒因子的相互关系、细胞种类等因素。
Influenza viruses induce apoptosis through mechanisms involving the interplay of cellular and viral factors that may depend on the cell type.
目的探讨小儿皮肤血管瘤各阶段肿瘤坏死因子相关凋亡诱导配体(TRAIL)的表达与细胞增殖和凋亡的关系。
Aim: to investigate the relationship between the expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), cell proliferation and apoptosis in children's skin hemangioma.
目的:探讨肿瘤坏死因子相关凋亡诱导配体(TRAIL)联合化疗药物治疗神经母细胞瘤(NB)的作用及其可能机制。
Objective: To explore the role of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL) combined with chemotherapeutic agents in treating neuroblastoma(NB) and the possible mechanism.
这和最近的研究是一致的,该研究表明卵母细胞成熟抑制因子能诱导用TNF处理的人类神经多肽的凋亡而不从线粒体中释放出来(7)。
This is in accord with a recent study that shows Omi can induce apoptosis in human neutrophils treated with TNF- without being released from the mitochondria (7).
肿瘤坏死因子相关的凋亡诱导配体(TRAIL)能选择性诱导肿瘤细胞凋亡。
TNF related apoptosis inducing ligand (TRAIL) can induce specific apoptosis of cancer cells.
细胞凋亡的发生受胞外或胞内的多种刺激源所诱导,其中热激蛋白是细胞凋亡的调控因子之一。
Apoptosis is induced by an array of extra - or intracellular stimuli and regulated by a variety of proteins including the heat shock proteins (HSPs).
肿瘤坏死因子相关诱导凋亡配体(TRAIL)是TNF家族中的一个新型凋亡分子。
TNF related apoptosis inducing ligand (TRAIL) is a newly identified member of the tumor necrosis factor (TNF) family.
背景与目的:肿瘤坏死因子相关凋亡诱导配体(tumornecrosisfactor-relatedapoptosisinducingligand,TRAIL)有广谱的抗瘤作用,且对正常组织细胞无毒性,因此有望应用于肿瘤基因治疗。
BACKGROUND & OBJECTIVE: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells.
目的探讨脂多糖(LPS)、巨噬细胞表达肿瘤坏死因子相关凋亡诱导配体(TRAIL)和肝细胞凋亡的相互关系。
Objective to investigate the influence of lipopolysaccharide (LPS) on macrophages expressing TNF-alpha related apoptosis induced-ligand (TRAIL) and its relation to apoptosis of HepG2 cell line.
CD4 7是T细胞活化的共刺激因子,活化T细胞凋亡过程,诱导T细胞无反应性,加强TCR信号传导的效率;
CD47 induces costimulatory signals on activation of T cell, T cell apoptosis and T cell anergy and enhances the efficiency of TCR signaling;
目前对这一现象有四种解释:ROS活化核转录因子KB并诱导核转录因子-KB表达,导致细胞凋亡;
At present, the explanations for this phenomenon are: 1) ROS activated nuclear factor-KB and induction of the expression of nuclear factor-KB; 2) mitochondria-mediated cell apoptosis;
目的:探讨肿瘤坏死因子相关细胞凋亡诱导配体(TRAIL)对人卵巢癌细胞株体外生长抑制作用。
Objective: the study is to find out the inhibition action of TNF-related apoptosis-inducing ligand or APO-2ligand (TRAIL) on ovarian carcinoma cell line cultured in vitro.
目的:探讨肿瘤坏死因子相关诱导凋亡配体(trail)蛋白和顺铂协同抑制横纹肌肉瘤细胞生长和诱导凋亡作用及其机制。
AIM: to study the synergistic induction of apoptosis by TRAIL and cisplatin in rhabdomyosarcoma cells and investigate the role of mitochondrial membrane potential and caspase-3 in this process.
目的:探讨肿瘤坏死因子相关诱导凋亡配体(trail)蛋白和顺铂协同抑制横纹肌肉瘤细胞生长和诱导凋亡作用及其机制。
AIM: to study the synergistic induction of apoptosis by TRAIL and cisplatin in rhabdomyosarcoma cells and investigate the role of mitochondrial membrane potential and caspase-3 in this process.
应用推荐