分子伴侣和蛋白酶可有效地调控多肽链的正确折叠。
Quality control over protein structure and function depends on the presence of molecular chaperones and proteases, which prevent aggregation.
这种‘分子伴侣’将会保持身体组织的稳定，并也会影响身体的其他部位。
These "molecular chaperones," if you will, keep tissues stable and also influence other areas of the body and brain, he said.
分子伴侣能解救构象性疾病，使晶状体重要的代谢酶‘起死回生’。
Molecular chaperone may rescue the conformational diseases and revive the inactive enzymes in lens.
目的初步探讨紫外线辐射所致皮肤细胞分子伴侣蛋白质组整体变化规律。
Objective To reveal the proteomic change of molecular chaperone in skin cell induced by UV radiation.
分子伴侣一词最初是指一类在细胞核内介导蛋白和核酸相互作用的生物分子。
The term "molecular chaperone" was originally used to describe a class of biomolecules, which mediate interactions between nuclear acids and proteins in the nucleus.
近年来深入研究蛋白质氧化折叠机制以及分子伴侣在蛋白质质量控制中的作用。
Recently studies on mechanism of oxidative protein folding and the role of molecular chaperones in protein quality control.
而利用分子伴侣的协助折叠特性进行的蛋白质复性技术正成为这一领域的研究热点。
Some kinds of molecular chaperone systems and their functions as well were reviewed in this paper.
近十几年来集中在蛋白质折叠研究，在国内开辟了分子伴侣和折叠酶研究的新方向。
Over the last decade focused on the study of protein folding, opened up a new direction for molecular chaperone and folding enzymes in China.
研究了细胞内存在的分子伴侣、蛋白质聚集和大分子拥挤环境对蛋白质折叠的影响。
The effects of molecular chaperones, protein aggregation and macromolecular crowding on protein folding have been studied.
钙网蛋白也作为内质网的分子伴侣起作用，以确保新合成糖蛋白的正确折叠和质量控制。
Calreticulin also functions as an er chaperone that ensures proper folding and quality control of newly synthesized glycoproteins.
卡马西平处理可以使HSP90乙酰化水平升高，并且破坏HSP90的分子伴侣功能。
Cabamazepine treatment could induce a higher acetylation level of HSP90 and destroy its chaperon function.
蛋白的折叠大多需要分子伴侣的协助才能完成，其中有两类分子伴侣对蛋白的折叠有重要的影响。
The properly folding of most heterologous proteins need the helper molecular chaperones. There are two kinds of molecular chaperones playing critical roles in the folding of protein in e.
蛋白的折叠大多需要分子伴侣的协助才能完成，其中有两类分子伴侣对蛋白的折叠有重要的影响。
There are two kinds of molecular chaperones playing critical roles in the folding of protein in E. coli.
细胞对这种应激的反应是增加一系列内质网分子伴侣如GRP94、GRP78和PDI等的表达。
Normal cells respond to ER stress by increasing transcription of genes encoding ER-resident molecular chaperones such as GRP94, GRP78 and PDI to facilitate protein folding.
方法根据人工分子伴侣对重组蛋白质的复性机理，采用人工分子伴侣方法应用于重组内抑素的复性。
Methods Based on the reactive principle of molecular chaperone, we adopted an artificial molecular chaperone-assisted refolding method for recombinant endostatin refolding.
分子伴侣机制的打断、衰老与疾病有关，缺陷的分子伴侣或分子伴侣样蛋白参与了分子伴侣病的发生。
The disruption of chaperoning mechanisms contributes to aging and disease, and defects in genes encoding chaperones or chaperone-like molecules contributes to the genesis of chaperonopathies.
研究人员了解到，次氯酸不会像对待多数蛋白那样破坏Hsp33，实际上反而加速分子伴侣开启功能。
The researchers learned that hypochlorite, rather than damaging Hsp33 as it does most proteins, actually revs up the molecular chaperone.
然后按照试验设计，考察不同浓度组成的人工分子伴侣体系对不同浓度鸡IL-18重组蛋白复性率的影响。
Then according to experiment design, the effects of rChIL-18 protein refolding yield at different densities were investigated by the systems of artificial chaperone at different densities.
CHIP的特殊结构特征使其成为沟通分子伴侣与泛素-蛋白酶体通路之间的桥梁，是蛋白质量控制系统的重要中介分子。
The special characteristics of CHIP make it become the bridge of molecular chaperone system and ubiquitin-proteasome pathway.
钙存储于内质网(ER)，在内质网内与钙离子结合分子伴侣如钙联接蛋白和钙网蛋白缓冲，并通过IP3受体通道释放(1)。
Calcium is stored in the endoplasmic reticulum (er), where it is buffered by calcium binding chaperones such as calnexin and calreticulin, and is released via the IP3 Receptor channel (1).
线粒体中的抑制素主要以膜结合环复合物的形式存在且在蛋白合成和转运过程中作为分子伴侣维持线粒体蛋白的稳定性(3,4)。
In mitochondria prohibitins mainly exist as membrane-bound ring complexes and function as chaperones maintaining mitochondrial protein stability during protein synthesis and transportation (3, 4).
事实证明，作为一种特异的分子伴侣，HSP90除在细胞正常生长和应急保护中具有重要生理功能外，还与信号传导、细胞周期调控、激素应答等细胞内重要生理过程有关。
In fact, as a specific molecular chaperone, HSP90 proteins are possibly involved in many important physiological processes such as signal transduction, cell cycle regulation and hormone response.
可能有一个伴侣分子刚好在那，或者它可能是另外一个A分子。
Could be a chaperone molecule that just happens to be there. Or it could be another molecule of a.
一个社区活跃分子给他们的花长时间工作的伴侣创造了新的社会机会。
A partner who is an active community volunteer creates new social opportunities for a spouse who spends long hours at work.
此复合体中P23作为HSP90的伴侣分子，能够和HSP90特异性结合，调节HSP90与ATP或ADP结合的形式而达到结合或释放靶蛋白的功能。
P23, as one co-chaperone of HSP90, could bind to HSP90 specially, let HSP90 bind or release the target protein by regulating the form of the HSP90 binding with ATP or ADP.
在环球，我们和伴侣及盟友一路或抓住或击毙了数十名基地可怕分子，个中包罗一些911变乱的始作俑者。
And around the globe, we worked with our friends and allies to capture or kill scores of al Qaeda terrorists, including several who were a part of the 9/11 plot.
在环球，我们和伴侣及盟友一路或抓住或击毙了数十名基地可怕分子，个中包罗一些911变乱的始作俑者。
And around the globe, we worked with our friends and allies to capture or kill scores of al Qaeda terrorists, including several who were a part of the 9/11 plot.
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