结论药代动力学和药效学结果证明，三七总皂苷鼻腔给药制剂具有很好的开发前景。
Conclusion The results of pharmacokinetics and pharmacodynamics demonstrated that PNS intranasal preparation has a pretty prospect to develop.
方法：采用高效液相色谱法测定我们制备的三七总皂苷分散片和血栓通制剂的溶出度。
METHODS: The dissolution rates of Radix Notoginseng total Saponin Dispersible tablets and Xueshuantong preparation were determined by HPLC.
主要观察指标：三七总皂苷对阿尔茨海默病大脑胆碱能神经元分布和胆碱乙酰基转移酶的影响。
MAIN OUTCOME MEASURES: Effect of PNS on distribution of cholinergic neuron and ChAT content in cerebral tissue of AD rat models.
主要观察指标：三七总皂苷对阿尔茨海默病大脑胆碱能神经元分布和胆碱乙酰基转移酶的影响。
MAIN OUTCOME MEASURES: Effect of PNS on distribution of cholinergic neuron and ChAT content in cerebral tissue of AD rat models.
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