比较了氯乙酰氯和溴乙酰溴对中间体及硝基安定收率的影响。
The effect of chloroacetyl chloride and bromoacetyl bromide on yields of intermediates and nitrazepam was compared.
介绍了氯乙酰氯的性质、标准、用途、生产工艺及其下游产品的合成方法和应用领域。
The character, standard, use and production process of chloracetyl chloride was introduced. In addition, the synthetic process and application of it's downstream products was introduced too.
西司他丁钠的合成以乙酰乙酸乙酯和1-溴-5-氯戊烷为原料，经活性亚甲基烃化、成肟和水解3步反应得7-氯-2-氧庚酸乙酯；
The synthesis of Cilastatin sodium started from ethyl acetoacetate and 1-bromo-5-chloropentane, through 3 steps to produce ethyl 7-chloro-2-oxoheptanoate;
西司他丁钠的合成以乙酰乙酸乙酯和1-溴-5-氯戊烷为原料，经活性亚甲基烃化、成肟和水解3步反应得7-氯-2-氧庚酸乙酯；
The synthesis of Cilastatin sodium started from ethyl acetoacetate and 1-bromo-5-chloropentane, through 3 steps to produce ethyl 7-chloro-2-oxoheptanoate;
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