目的探讨内皮素- 1 (et - 1)在高血压性脑出血(HCH)发病机制中的作用。
Objective To evaluate the role of endothelin-1 (ET-1) in the pathogenesis of hypertensive cerebral hemorrhage (HCH).
方法在双肾双夹法复制肾血管性高血压模型的基础上,以胶原酶加肝素脑内注射诱发脑出血,建立高血压性脑出血大鼠模型。
Methods On the base of renovascular hypertensive rats (RHR) model, the hypertensive cerebral hemorrhage rat model was induced by injecting collagenase and heparin into the brain.
方法在双肾双夹法复制肾血管性高血压模型的基础上,以胶原酶加肝素脑内注射诱发脑出血,建立高血压性脑出血大鼠模型。
Methods On the base of renovascular hypertensive rats (RHR) model, the hypertensive cerebral hemorrhage rat model was induced by injecting collagenase and heparin into the brain.
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