为了利用这种基质金属蛋白酶，钱博士将他的荧光染料和一些正电荷一同连接在一个小的发夹形状的蛋白质分子的一端。
To make use of the MMPs, Dr. Tsien attaches his fluorescent dye, along with some positive charges, to one side of a small hairpin-shaped protein molecule.
现就近年来基质金属蛋白酶和冠心病的研究进展作一综述。
The aim of this article is to brief review the recent study on MMPs and CHD.
目的探讨基质金属蛋白酶及其抑制因子与组织纤维化的关系。
Objective to discuss the relationship between matrix metalloproteinases and its tissue inhibitors and tissue fibrosis.
目的：评价基质金属蛋白酶抑制剂临床应用的疗效与安全性。
OBJECTIVE: to evaluate the efficiency and safety of matrix metallo-proteinase inhibitor in clinical application.
这是一系列尤其容易被基质金属蛋白酶切断的氨基酸(蛋白质的基石)序列。
This is a sequence of amino acids (the building blocks of proteins) that is particularly vulnerable to the cutting action of MMPs.
布洛芬对软骨降解及基质金属蛋白酶13和组织蛋白酶k水平无明显影响。
Ibuprofen had no obvious effect on articular cartilage degradation and decreasing the levels of matrix metalloproteinase 13 and cathepsin K.
基质金属蛋白酶是一类结构相关的内肽酶家族，能够降解细胞外基质成分。
The matrix metalloproteinases are a family of structurally related endopeptidases, they have the ability to degrade all components of extracellular matrix.
细胞外基质是构成血管壁的主要成分，其代谢平衡受基质金属蛋白酶的调节。
Extracellular matrix is the main composition which constitute blood vessel wall, its balance of metabolism is to suffer the matrix metalloproteinases to regulate.
结论：基质金属蛋白酶的高表达有助于判断宫颈癌的转移潜能并指导临床治疗。
Conclusion the positive expression of MMPs can be used to estimate the metastatic potentiality and guide the clinical treatment.
明胶酶谱法测量血液循环中基质金属蛋白酶- 9 (MMP - 9)水平。
Gelatin zymography was used to measure blood levels of circulating matrix metalloproteinase-9 (MMP-9).
基质金属蛋白酶家族是锌依赖蛋白酶，是参与正常细胞外基质代谢的重要酶类。
Matrix metalloproteinases(MMPs )are a family of zinc-dependent proteinases involved in the degradation of the extracellular matrix.
有几种酶——如基质金属蛋白酶和胶原酶——可能派上用场，但矫枉过正也会有风险。
Several enzymes, such as matrix metalloproteinases and collagenases, might do the job, but overdoing it could be risky.
目的：探讨基质金属蛋白酶- 9 (MMP - 9)在心肌再灌注损伤中的作用。
AIM: To study the roles of matrix metalloproteinase-9 (MMP-9) in the myocardial reperfusion injury.
目的：探讨基质金属蛋白酶-9（MMP9）和CD147在乳腺癌中的表达及意义。
Objective:To observe the expression and its significances of MMP9 and CD147 protein in breast cancer.
目的：探讨结直肠癌环氧化酶- 2和基质金属蛋白酶- 7的表达与侵袭、转移的关系。
Objective: To investigate the expression of COX-2 and MMP-7 and their influence on invasion and metastasis in colorectal cancer.
结果患者血清基质金属蛋白酶-9水平高于健康对照组，差异有显著性意义（P<0.01）；
Results The serum levels of MMP-9 in IPF were significantly higher than that of healthy control, with significant difference (P<0.01).
目的：探讨基质金属蛋白酶2 (MMP - 2)在体外构建的C6细胞侵袭模型中的作用。
Objective: To study the function of matrix metalloproteinase-2 (MMP-2) in the selected C6 cells invasion model in vitro.
目的探讨膜型基质金属蛋白酶-1在人脑胶质瘤中的表达及其与肿瘤生物学行为和预后的关系。
Objective To investigate the expression of membrane type-1 matrix metalloproteinase(MT1-MMP) in human glioma and its relationship to clinicopathological factors and prognosis of glioma patients.
目的探讨基质金属蛋白酶-9 (MMP - 9)在乳腺癌及癌旁正常组织中的表达及意义。
Objective To approach the expression of matrix metalloproteinase (MMP) -9 and its significance in breast carcinoma and corresponding non-tumor normal tissues.
感染引发早产的机制与前列腺素的合成、细胞因子的异常分泌、基质金属蛋白酶活性增加等有关。
The mechanism of premature delivery caused by infection involves in increased prostaglandin synthesis, abnormal secretion of cytokines and increased activity of matrix metalloproteinases.
目的：探讨碱性成纤维细胞生长因子对基质金属蛋白酶表达的影响及其在球囊术后再狭窄中的作用。
Objective: To investigate the effect of basic fibroblast growth factor on matrix metalloproteinases and restenosis after PTCA .
目的探讨脑星形细胞瘤瘤周水肿表观扩散系数（ADC）值与基质金属蛋白酶（MMP-9）表达的关系。
Objective To discuss the correlation between MMP-9 expression levels and ADC values in peritumoral edema of cerebral astrocytoma.
目的：观察基质金属蛋白酶- 7 (MMP - 7)蛋白在鼻咽癌中的表达及与肿瘤侵袭转移的关系。
Objective: To observe the expression of matrix metalloproteinase-7 (MMP-7) in nasopharyngeal carcinoma and it's significance in metastasis.
目的：探讨基质金属蛋白酶10 (MMP10)基因及其蛋白在人自然流产蜕膜中的表达水平及临床意义。
Objective: To discuss expression levels of MMP10 gene and protein in human spontaneous abortion deciduas and its significance in clinic.
目的：检测肝细胞癌患者血清血管内皮生长因子与基质金属蛋白酶- 9含量并分析与临床分期的相关性。
Objective to detect the concentration of serum vascular endothelial growth factor and matrix metalloproteinase-9 in hepatocellular carcinoma and analyze their relation with the clinical stages.
为了利用这种基质金属蛋白酶，钱博士将他的荧光染料和一些正电荷一同连接在一个小的发夹形状的蛋白质分子的一端。
To make use of the MMPs Dr Tsien attaches his fluorescent dye, along with some positive charges, to one side of a small hairpin-shaped protein molecule.
方法采用酶联免疫吸附法对40例特发性肺纤维化患者和30例健康人血清基质金属蛋白酶- 9进行测定。
Methods The serum level of MMP-9 in 40 patients with IPF and 30 healthy subjects was measured by ELISA.
目的观察局部动脉壁剪切力改变对基质金属蛋白酶2 (MMP - 2)表达的影响及其与动脉瘤形成的关系。
Objective To observe the relation between the change of arterial wall shear stress and the expression of matrix metalloproteinase 2 (MMP-2), and analyze its role in aneurysm formation.
目的探讨急性脑梗死患者血清基质金属蛋白酶- 9 (MMP - 9)及外周白细胞(WBC)计数的变化。
Objective To study the changes of serum MMP-9 concentration and WBC count in acute cerebral infarction patients.
目的探讨组织蛋白酶D（CD）与基质金属蛋白酶-9（MMP-9）在人类口腔鳞癌（OSCC）中的表达意义。
Objective To investigate the expression and the significance of cathepsin D(CD) and matrix metalloproteinase-9(MMP-9) in oral squamous cell carcinoma(OSCC).
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