我必须指出新药的试验很昂贵，而且你永远不能保证成功。
I must point out that trials of new medicine are expensive and you can never guarantee success.
为了公平起见，必须指出高跟鞋也有好的一面。
For the sake of fairness, it must be noted that there is a positive side to high heels.
必须指出的是，增加工作灵活性，但并不鼓励员工全天候工作。
It's important to note that the increased flexibility didn't encourage them to work around the clock.
必须指出的是，其他因素，如火山微粒或地球接收到的阳光量的变化，可能已经潜在地影响了气候。
It is important to note that other factors, such as volcanic particulates or variations in the amount of sunlight received by the Earth, could potentially have affected the climate.
我们必须指出一个更大的困难。
必须指出，这样的错误不能再犯。
It must be pointed out that mistakes of this kind should not be repeated.
因此，一个确认器必须指出这些问题。
必须指出的是，Ming仍处于开发阶段。
必须指出，这种区域划分并无严格的地理界线。
It should be pointed out that these designations are not hard and fast geographical boundaries.
我必须指出，数学模型并不是越多越好。
I have to disagree that it is just a case of more is better.
我必须指出，左边电极充负电,右边电极充正电。
And the way I have this configured, the left electrode is going to be charged negatively and the right electrode is going to be charged positively.
但我必须指出的是，市场并不能解决社会问题。
But I do have to say this: the market does not solve social problems.
不幸的是，必须指出，有时候这一优点不值得付出努力。
And it's worth pointing out that, unfortunately, sometimes the benefit here isn't worth the effort.
必须指出，并非所有人都同意他对历史的这种解读。
Not everyone, it must be said, agrees with this interpretation of history.
我必须指出的是，大部分女性对长期的恋爱关系是坚决支持的。
I must point out, most women are usually hard-wired for long-term relationships.
首先，必须指出，保加利亚本身是那么一种肮脏的地方。
First, it must be said that Bulgaria itself is kind of a dirty place.
事实上，我必须指出整合代码片段的想法不是我们的原创。
Indeed, it's important to point out that we did not invent the idea of working with fragments.
必须指出的是，本文中的讨论没有任何贬低rss的目的。
It is important to point out that it is not the intent of this discussion to disparage RSS in any way.
必须指出的是皇家马德里的前三个进球都是巴列卡诺的失误造成的。
It must also be pointed out that Real Madrid's first three goals were all the direct result of mistakes by Vallecano.
一旦我们有了文化评估的结果，我们必须指出如何改变文化。
Once we have the results of a cultural assessment, we must then figure out how to change the culture.
这里必须指出的是，自签名证书与CA签名证书的工作方式完全相同。
I should mention at this point that self-signed certificates work in exactly the same way as ca signed certificates.
我们必须指出，假装不知道穷人的困境完全是出于无知的不负责任的表现。
We must point out that feigning ignorance of the plight of poverty-stricken people is simply an irresponsible act on the part of ignorance.
必须指出的是，多数XQuery实现都提供了自己的更新机制。
It is important to note that most XQuery implementations provide an update mechanism of their own.
这意味着你必须指出,立体图形的底部的曲面，和立体图形的顶部曲面？
So, that means you have to figure out what's the bottom surface of your solid, and what's the top surface of your solid?
例如，需求必须指出一个已有参考体系结构中没有关联的新中间件服务。
For example, requirements might dictate a new middleware service not yet articulated in the existing reference architecture.
一旦找到错误，它必须指出错误的真实原因，最好是提供人们能够理解的错误消息。
When it finds a mistake, it must point to the true reason for it, preferably with an error message that humans understand.
但如今，占星学不过是游乐场的游戏罢了，而天文学成为了必须指出其中区别的科学！
Today though, astrology has turned into nothing more than a fairground act and astronomy has turned into a science having to point out the difference!
但如今，占星学不过是游乐场的游戏罢了，而天文学成为了必须指出其中区别的科学！
Today though, astrology has turned into nothing more than a fairground act and astronomy has turned into a science having to point out the difference!
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