遗传性结直肠癌大约占所有结直肠癌的15%。
Hereditary forms can account for up to 15% of all colorectal cancers.
【译】在转移性结直肠癌影响总生存期KRAS测试吗？
Does KRAS Testing in Metastatic Colorectal Cancer Impact Overall Survival?
目的探讨同期治疗同时性结直肠癌肝转移的微创手术方法。
Objective To investigate the minimal invasive surgery for simultaneous treating synchronous colorectal liver metastasis.
目的：探讨西妥昔单抗联合化疗治疗转移性结直肠癌的疗效和不良反应。
Objective: to determine the therapeutic effect and toxicity of cetuximab and chemotherapy agents in metastatic colorectal cancer.
目的了解国人遗传性非息肉病性结直肠癌（HNPCC）的临床病理及分子遗传学特征。
Objective To investigate the clinicopathological and molecular genetic characteristics of Chinese hereditary nonpolyposis colorectal cancer (HNPCC) pedigrees.
结果50例结肠扩大切除术的患者没有一例被诊断出患有异时性结直肠癌（发病率0.0；
Results None of 50 subjects who had extensive colectomy was diagnosed with metachronous CRC (incidence rate 0.0;
评价应用临床信息，病理学特点和微卫星分析来鉴别具有突变子表型的散发性结直肠癌患者的可行性。
To assess the feasibility of using clinical informations, pathological features, immunohistochemistry and microsatellite analysis to identify patients with the mutator phenotype.
例如，委员会使用的关于单克隆抗体西妥昔单抗和帕尼单抗(它们抑制转移性结直肠癌的表皮生长因子受体egfr)的数据。
For example, the Panel used data for the monoclonal antibodies cetuximab and panitumumab, which inhibit the EGF receptor (EGFR) in metastatic colorectal cancer.
结直肠癌占肿瘤相关性死亡的多数。
Colorectal cancer accounts for a large number of tumor-related deaths.
ASGE筛查指南推荐，刚年满50岁、有发生结直肠癌一般风险的无症状性男性和女性，应该开始结直肠癌筛查。
ASGE screening guidelines recommend that, beginning at age 50, asymptomatic men and women at average risk for developing colorectal cancer should begin colorectal cancer screening.
目的观察贝伐单抗与化疗药物联合用于晚期结直肠癌一线治疗的近期疗效和安全性。
OBJECTIVE To evaluate the efficacy and safety of bevacizumab when added to first-line irinotecan-based chemotherapy in patients with metastatic colorectal cancer.
结论：初诊不能切除的结直肠癌肝转移患者行缩小性化疗后再次切除，其治愈率可达16%。
Conclusion: Cure can be achieved overall in 16% of patients with initially unresectable CLM resected after downsizing chemotherapy.
结论：吸烟与结直肠癌发病率和死亡率之间存在显著相关性。
Conclusion Cigarette smoking is significantly associated with colorectal cancer incidence and mortality.
目的探讨人粪便中分泌型卷曲相关蛋白2（SFRP2）基因甲基化分析用于结直肠癌（CRC）早期诊断的可行性。
To evaluate the possibility of methylation analysis of secreted frizzled-related protein gene 2(SFRP2)in feces for screening early colorectal cancer (CRC).
方法：我们随机分组表皮生长因子受体阳性、转移性、不可切除结直肠癌患者接受FOLFIRI单独化疗或联合西妥昔单抗化疗。
Methods We randomly assigned patients with epidermal growth factor receptor-positive colorectal cancer with unresectable metastases to receive FOLFIRI either alone or in combination with cetuximab.
随着一级亲属患结直肠癌人数增加，结肠癌患者复发或死亡风险降低和家族史呈更强的相关性。
The reduction in risk of cancer recurrence or death associated with a family history became stronger as the number of affected first-degree relatives increased.
目的探讨印度墨汁用于腹腔镜结直肠癌根治术中定位的有效性。
Objective To evaluate the effectiveness of endoscopic India ink marking technique in laparoscopic colorectal cancer surgery.
背景：结直肠癌根治性手术后复发仍然是一个重要的临床问题并且预后较差。
Background: Recurrence after potentially curative surgery for colorectal cancer remains a significant clinical problem and has a poor prognosis.
方法：回顾性分析1990 ~ 2002年收治的64例65岁以上的结直肠癌病人的外科治疗资料。
Methods To retrospectively analyse the experience of surgical treatment with colorectal carcinoma in 64 patients over 65 years of age from 1990 ~ 2002.
目的探讨早期结直肠癌的诊断方法及微创治疗的可行性。
Objective To explore the diagnostic methods of early colorectal carcinoma and the feasibility of minimally invasive treatment.
结、直肠癌在老年、中年组的发病率明显高于其他年龄组； 中年组肛周病变、炎症性肠病的发病率明显高于其他年龄组。
The morbidity of large bowel cancer in the elderly and middle-aged groups were obviously higher than that of the other age groups.
方法：荧光标记的多态性微卫星引物d10s1265与83例结直肠癌的肿瘤和正常组织进行PCR反应。
Methods: D10S1265, a fluorescent labeled polymorphic microsatellite marker, was analyzed in 83 cases of sporadic CRC and normal tissue DNA by PCR.
目的：观察晚期结直肠癌应用复方苦参注射液联合FOLFOX - 4方案治疗的安全性及疗效。
OBJECTIVE: To evaluate the efficacy and safety of Compound Matrine injection in combination with FOLFOX-4 chemotherapy in the treatment of advanced colorectal cancer.
方法：回顾性分析21例腹腔镜辅助结直肠癌切除病例的临床资料。
Methods: Data of 21 cases of colorectal carcinomas that underwent laparoscopic assisted resections in our hospital were retrospectively reviewed.
结论：老年结直肠癌发病具有隐匿性，应对可疑病例进行详尽检查，提高老年结直肠癌的早期诊断率。
Conclusion: Because of occult onset, elaborative examination is essential for suspicious cases to elevate the early diagnostic rate of colorectal cancer in the elder.
这些结果表明，防止一例结直肠癌需要筛查的人数为191名，防止一例结直肠癌相关性死亡需要筛查的人数是489名。
These results suggest that the number of individuals requiring screening to prevent one CRC is 191 and to prevent CRC-related death the number is 489.
这些结果表明，防止一例结直肠癌需要筛查的人数为191名，防止一例结直肠癌相关性死亡需要筛查的人数是489名。
These results suggest that the number of individuals requiring screening to prevent one CRC is 191 and to prevent CRC-related death the number is 489.
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