因此，研发抗结核分枝杆菌持留菌的药物，对缩短抗结核治疗疗程，减少耐药性发生意义重大。
There is an urgent need and significant interest in developing new drugs that target the persistent bacteria to shorten the therapy and reduce the drug resistance.
结核病疫情日益严重，尤其是耐药结核分枝杆菌的出现，使抗结核化疗药物面临严峻的挑战。
The epidemic situation of tuberculosis is more and more severe, especially drug-resistant mycobacterium tuberculosis make antituberculous chemical drug facing grim challenge.
结核病疫情日益严重，尤其是耐药结核分枝杆菌的出现，使抗结核化疗药物面临严峻的挑战。
The epidemic situation of tuberculosis is more and more severe, especially drug-resistant mycobacterium tuberculosis make antituberculous chemical drug facing grim challenge.
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