肿瘤细胞存在一种叫做整合素的分子。
本文将就整合素和卵巢癌侵袭转移研究现状进行综述。
This article reviews and gives summary of current research on integrin and the metastasis of ovarian cancer invasion.
病毒颗粒可以包裹一种多肽,能够和整合素特异性结合。
The virus particles could be coated externally with peptides that bind to integrins.
在肿瘤血管生成过程中,活化血管内皮细胞整合素表达明显上调。
Integrin is often significantly up-regulated in activated endothelial cells during tumor angiogenesis.
目的探讨光化学疗法对内皮细胞管腔形成能力及整合素表达的影响。
Objective to investigate the effects of photochemotherapy on the angiogenic ability of endothelial cells and expression of integrin.
提示整合素连接激酶可能涉及到老龄肾脏的纤维化过程或衰老过程。
The results suggested that ILK might be involved in fibrotic process or senescent process in aging kidney.
目的研究去整合素对体外培养的人眼晶状体上皮细胞生长的抑制作用。
Objective to study the inhibitory effect of disintegrin on adhesion and migration in cultured human lens epithelial cells (LECs) in vitro.
目的研究硬皮病成纤维细胞整合素表达对成纤维细胞合成原胶原的影响。
Objective Investigation of the effect of integrin on fibroblasts from scleroderma in the production of procollagen.
探讨了整合素、细胞骨架、FAK在大肠癌侵袭转移中的信号转导机制。
And the mechanism of the signal transduction among integrin, cytoskeletons and FAK in the invasion and metastasis of CRC were explored.
拮抗整合素能抑制再狭窄的形成,这可能成为开发防治再狭窄新药的方向。
Antagonists of integrins could inhibit the development of restenosis, which might provide insight into the use of new drugs to treat restenosis.
整合素是普遍存在于细胞表面的跨膜糖蛋白,其主要功能是粘附和信号传递。
Integrins, present essentially on the surface of cells, are transmembrane glycoproteins that function as cell adhesion and transduction of signals.
肿瘤细胞表面CAR和整合素的表达水平决定了腺病毒对肿瘤细胞的感染效率。
The infection efficiency of adenovirus is determined by the levels of CAR and integrin on cancer cells.
整合素是一类介导细胞与细胞外基质及细胞与细胞间黏附的细胞黏附分子受体。
Integrin is an important receptor of cellular adhesion molecules, which mediates the adhesion between cell and cell or cell and extracellular matrix.
在昆虫中整合素对果蝇的生长发育及一些鳞翅目昆虫的先天性免疫反应起重要作用。
Integrin played important roles in development of Drosophlia and innate immune response of some lepidoptera insects.
结论:肿瘤细胞表面CAR和整合素的表达水平决定了腺病毒对肿瘤细胞的感染效率。
Conclusion: the infection efficiency of adenovirus is determined by the levels of CAR and integrin on cancer cells.
结论降低硬皮病成纤维细胞整合素的表达,可从转录水平抑制成纤维细胞合成原胶原。
Conclusion Overproduction of procollagen may be inhibited in the level of transcription by lowering the expression of integrin on fibroblasts in scleroderma.
整合素是细胞表面介导细胞-细胞间以及细胞-细胞外基质间黏附作用的主要黏附分子。
Integrins are an important family of cell surface receptors that mediate the adhesion of cells to each other and to the extracellular matrix.
目的探讨血清去整合素-金属蛋白酶8 (ADAM8)水平对肺癌诊断及预后的价值。
Objective To investigate the value of serum ADAM8 level in diagnosis and prognosis of lung cancer.
本发明涉及环肽类似物及其环化方法,旨在提供一种整合素配体环肽类似物及其环化方法。
The invention relates to a cyclopeptide analog and a cyclization method thereof, which aims at providing an integrin ligand cyclopeptide analog and a cyclization method thereof.
基底膜的组成成分通过和细胞表面受体整合素相互作用,在调节肿瘤转移的过程中发挥了重要作用。
The component of basement membrane plays important role in regulating tumor metastasis by interacting with cell surface receptor integrins.
OPN通过与其主要的受体整合素和CD_(44)相互作用,参与多组织、多器官的生理病理过程。
Previous research found that OPN was involved in physiological and pathological processes in variety of tissues and organs through bindinging with integrins and CD_(44) receptors.
整合素和细胞骨架在力信号转化为细胞内生化信号,进而引发相应的生理或病理反应中起着重要作用。
Integrins and cytoskeleton play important role in the conversion of mechanical signals into intracellular biochemical signals followed by physiological or pathological responses.
整合素是一类广泛存在于细胞表面的粘附分子,介导细胞—细胞及细胞—细胞外基质间的粘附及信息传导。
Integrin, a kind of adhesion molecule generally exists on the cell surface, mediates adhesion and information transmissions between cell-cell and between cell-extracellular matrix.
我们综述了RGD与整合素受体的相互作用,RGD生物活性的影响因素以及它在生物材料内皮化方面的应用。
In this review, the interaction of RGD peptides sequence and integrins, the influential factors of RGD peptides bioactivity and its application in endothelialization of biomaterials were discussed.
目的:探讨辛伐他汀对高脂诱导的大鼠肾组织整合素连接激酶(ILK)的表达及其对肾小管间质损害的影响。
AIM: To explore the effect of simvastatin on expression of integrin-linked kinase (ILK) and the injury of renal tubulointerstitium in the rats induced by high fat diet.
阻断整合素介导的白细胞黏附(尽管在实验模型中是有裨益的)在治疗人类的炎症性疾病上所获得的成功是有限的。
Blocking integrin-mediated leukocyte adhesion, although beneficial in experimental models, has had limited success in treating inflammatory diseases in humans.
细胞膜内一种称为整合素的蛋白质将每个细胞与基质相连,同时细胞内部的蛋白架构不断牵引着这些整合素,创建出一个拉紧的、协调的整体。
Each cell is linked to this matrix by proteins in its membrane called integrins, and the cell's internal protein skeleton is constantly tugging on these integrins to create a taut, tuned whole.
牛白细胞粘附缺陷病(BLAD)是一种常染色体单基因隐性遗传疾病,病因为白细胞表面整合素cd 18亚单位基因突变所致。
Bovine leukocyte adhesion deficiency (BLAD) is autosomal recessive disease. The pathogeny of BLAD is genic mutation of CD18-integrins on the leukocyte.
牛白细胞粘附缺陷病(BLAD)是一种常染色体单基因隐性遗传疾病,病因为白细胞表面整合素cd 18亚单位基因突变所致。
Bovine leukocyte adhesion deficiency (BLAD) is autosomal recessive disease. The pathogeny of BLAD is genic mutation of CD18-integrins on the leukocyte.
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