目的通过检测儿童急性白血病多药耐药基因及细胞凋亡调控基因表达水平的改变，分析不同类型白血病的主要耐药机制。

Objective To study the drug resistance in different types of acute leukemia in children, the expression of multidrug resistance gene and apoptosis-related genes were analyzed.

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目的探讨胰岛素样生长因子-Ⅰ（IGF-Ⅰ）及胰岛素样生长因子结合蛋白-3（IGFBP-3）在急性淋巴细胞白血病（ALL）儿童中检测的意义。

ObjectiveTo explore the detection significance of insulin-like growth factor-I(IGF-I), IGF-binding protein-3(IGFBP-3) in children with acute lymphoblastic leukemia(ALL).

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目的检测儿童急性淋巴细胞白血病细胞增殖性抗原表达情况，观察其与预后的关系。

Objective To study the expression of proliferative antigens in leukemic cells and the relationship between the cell proliferation activity and the prognosis.

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目的检测儿童急性淋巴细胞白血病细胞增殖性抗原表达情况，观察其与预后的关系。

Objective To study the expression of proliferative antigens in leukemic cells and the relationship between the cell proliferation activity and the prognosis.

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