气道重塑成为哮喘新的治疗靶点还有多远?
Long way to go before airway remodeling becomes therapeutic target in bronchial asthma?
这些改变称为气道重塑。
奇怪的是,由于肺疾病气道重塑的发病率和重要性,其病因是知之甚少。
Paradoxically, given the prevalence and importance of airway remodeling in lung disease, its etiology is poorly understood.
目的:探讨组胺受体拮抗剂对哮喘豚鼠气道重塑和酸碱平衡紊乱的防治作用。
AIM: to investigate the effect of histamine receptor antagonist on airway remodeling and acid-base imbalance in asthma of guinea pig.
目的:利用高分辨率CT (HRCT)探讨慢性稳定期哮喘患者的气道重塑。
Objective: To explore the airway remodeling in patients with chronic stable asthma by high-resolution ct (HRCT).
哮喘则是一种以气道重塑(可能影响疾病慢性程度和严重性)为特征的慢性炎症性疾病。
Asthma is a chronic inflammatory disease characterized by airway remodeling that might affect disease chronicity and severity.
结论VEGF在小鼠哮喘模型气道及肺内过度表达,并参与了哮喘的发病和气道重塑过程。
Conclusions VEGF was over-expressed in the murine model of asthma, and involved in angiogenesis and airway remodeling.
这个角度出发,总结了我们所知道的,我们需要了解气道的基底细胞,来评价他们的贡献,以正常和不正常的气道重塑。
This Perspective summarizes what we know, and what we need to know, about airway basal cells to evaluate their contributions to normal and abnormal airway remodeling.
孟鲁司特可能通过并影响VEGF及受体的表达影响气道炎症和气道血管重塑的病理生理过程。
MK may be effective in reducing allergic airway inflammation and airway remodeling through VEGF and VEGFR.
目的:研究慢性支气管炎(慢支)、肺气肿气道及肺部炎症在肺动脉重塑中的作用。
AIM: To study the effects of airway and pulmonary inflammation on pulmonary arterial remodeling in rats with chronic bronchitis (CB) and emphysema.
目的:研究慢性支气管炎(慢支)、肺气肿气道及肺部炎症在肺动脉重塑中的作用。
AIM: To study the effects of airway and pulmonary inflammation on pulmonary arterial remodeling in rats with chronic bronchitis (CB) and emphysema.
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