• 大部分患者不会滤泡性淋巴瘤非常肯定的。

    Most patients will not die from follicular lymphoma, and that's very reassuring.

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  • 目的讨论淋巴增生滤泡性淋巴瘤鉴别诊断

    Objective To discuss the differential diagnosis between tumor-like follicular hyperplasia and follicular lymphoma.

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  • 作者描述88CD5+滤泡性淋巴瘤临床病理学特征53例35例

    We describe the clinicopathologic features of 88 cases of CD5+ follicular lymphoma (53 men, 35 women;

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  • 目的系统评价大剂量化疗自体干细胞移植一线治疗滤泡淋巴瘤临床疗效安全

    ObjectiveTo assess the effectiveness and safety of high-dose chemotherapy following autologous stem cell transplantation in first-line treatment of follicular lymphoma.

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  • 除了代表潜在生物标记物外,伴有缺陷BCR信号细胞存在提供滤泡性淋巴瘤新的靶点

    In addition to representing a potential biomarker, the existence of cells with defective BCR signaling may provide new targets against follicular lymphoma. -jcl.

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  • 此外研究利妥单抗pembrolizumab联合来治疗复发滤泡性淋巴瘤

    Additionally, a phase II study is looking at the combination of rituximab and pembrolizumab (Keytruda) for patients with relapsed follicular lymphoma (NCT02446457).

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  • 自体干细胞移植性淋巴瘤线治疗中除临床试验之外不宜采用。(证据等级:中等)。

    Autologous stem cell transplantation has no role in first line therapy for FL outside a clinical trial (Strong, Moderate).

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  • 观察等待无症状晚期滤泡性淋巴瘤常用的策略,但是对于这些患者来说美罗华单药治疗也是一个选项。

    Watch and wait (WAW) is a common approach for asymptomatic, advanced stage follicular lymphoma (FL), but single-agent rituximab is an alternative for these patients.

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  • 我们研究旨在评价利妥单抗化疗一线治疗滤泡性淋巴瘤患者使用利妥昔单抗维持治疗2的疗效。

    We assessed the potential benefit of 2 years of rituximab maintenance after first-line treatment in patients with follicular lymphoma receiving a rituximab plus chemotherapy regimen.

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  • PI3K抑制剂idelalisibBTK抑制剂ibrutinib对复发滤泡性淋巴瘤显示出很好的潜力。

    The PI3K deltainhibitor idelalisib (Zydelig) and the BTK inhibitor ibrutinib (Imbruvica) have shown promise for patients with relapsed follicular lymphoma.

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  • 阐释滤泡性淋巴瘤患者免疫化疗作为一线治疗后使用利妥昔单抗维持治疗2能显著改善无进展生存(PFS)。

    INTERPRETATION: 2 years of rituximab maintenance therapy after immunochemotherapy as first-line treatment for follicular lymphoma significantly improves PFS.

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  • 期的CheckMate- 140试验正在探索nivolumab治疗经cd 20抗体治疗后进展的淋巴瘤

    The phase II CheckMate-140 trial is exploring nivolumab (Opdivo) for patients with follicular lymphoma following progression on a CD20 antibody and an alkylating agent (NCT02038946).

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  • 这种应答意义的,尽管霍奇金病那么高,但是依然很不错,”莱昂纳德,“问题是否专门针对滤泡性淋巴瘤来开发这种?”

    "These responses are meaningful, not as dramatic as we have seen in Hodgkin's, but it is meaningful," said Leonard. "The question is, 'can you develop this drug in follicular lymphoma?"

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  • 一个30例患者小规模研究中,pidilizumab加利妥单抗在复发滤泡性淋巴瘤中取得了66%的总有效率,其中大部分是完全缓解

    In a small 30-patient study, pidilizumabplus rituximab demonstrated an ORR of 66% in relapsed follicular lymphoma, which primarily consisted of complete responses.

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  • 2016年2月底,FDA批准对接受过利妥昔单抗治疗的淋巴瘤患者使用CD20单抗obinutuzumab和苯达莫司汀联合的方案。

    In late February 2016, the FDA approved the anti-CD20 agent obinutuzumab(Gazyva) in combination with bendamustine for patients with follicular lymphoma following rituximab-based therapy.

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  • B细胞淋巴瘤一种霍奇金淋巴瘤肿瘤疫苗是治疗是根据肿瘤细胞生物学特殊

    The cancer vaccines rely on a biological quirk of follicular B-cell lymphoma, which is a type of non-Hodgkin's lymphoma.

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  • 如果肿瘤初始治疗无效,你的治疗选择详见复发难治滤泡淋巴瘤的治疗部分。

    If your disease does not respond to initial treatment, your treatment options are detailed below under Treatment of Recurrent or Refractory Follicular Lymphoma.

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  • 如果肿瘤初始治疗无效,你的治疗选择详见复发难治滤泡淋巴瘤的治疗部分。

    If your disease does not respond to initial treatment, your treatment options are detailed below under Treatment of Recurrent or Refractory Follicular Lymphoma.

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