本文对恶性肿瘤的微卫星不稳定性作一综述。
The essay is an overview of the relation between microsatellite instability and malignant tumor.
目的：探讨头颈部鳞癌的微卫星不稳定性(msi)及杂合性丢失(LOH)。
AIM: To examine the microsatellite instability (MSI) and loss of heterozygosity (LOH) in head and neck squamous cell carcinomas (HNSCC).
众多学者认为，遗传物质的微卫星不稳定性可导致肿瘤的发生，尤其在恶性肿瘤的发生中有特殊作用。
There is still much debate on the distinct classes of genomic instability and their specific roles in the initiation of tumor formation, as well as in the progressive transition to a cancerous state.
多态性缺失是微卫星不稳定性的表现形式。
Loss of polymorphism is a special form of expression of microsatellite instability.
多态性缺失是微卫星不稳定性的表现形式。
Loss of polymorphism is a special form of expression of microsatellite instability.
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