开发选择性类固醇激素受体调节剂有望成为未来防治骨质疏松药物的研究方向。
To develop a new selective steroid receptor modulator is one of the targets in future study to treat osteoporosis.
结论RU486具有抗肿瘤作用，对不同类固醇激素受体状态的乳腺癌细胞其抗肿瘤作用的机制不同。
Conclusion RU486 has antitumor effect, but has different antitumor mechanism between steroid hormone receptor positive and negative breast cancer cell lines.
目的观察小鼠烧伤后早期类固醇受体辅活化子（SRC）蛋白表达的时相变化，初步探讨烧伤早期糖皮质激素抵抗的分子机制。
Objective To observe the changes of expression of steroid receptor coactivators(SRC) during the early stage in the burned mice, and the mechanism of glucocorticoid resistance(GCR).
在异型配子ZW胚胎中，雌激素受体、类固醇生成因子- 1和P 450芳香化酶基因的表达可刺激卵巢的形成。
While in the heterozygotic ZW embryo, expression of estrogen receptor, steroidogenic factor-1 and P450 aromatase might stimulate ovarian formation.
大多数雄激素非依赖性前列腺癌均高表达AR和核受体辅活化子、如转录中间因子2（TIF-2），ARA24、PIAS、类固醇受体辅活化子-1（SRC-1）等有力地支持了这个假说。
The "superactive AR"hypothesis was supported by the fact that the majority of AIPC expresses high level of AR and nuclear receptor(NR) coactivators, such as TIF-2, ARA24, PIAS, SRC-1.
大多数雄激素非依赖性前列腺癌均高表达AR和核受体辅活化子、如转录中间因子2（TIF-2），ARA24、PIAS、类固醇受体辅活化子-1（SRC-1）等有力地支持了这个假说。
The "superactive AR"hypothesis was supported by the fact that the majority of AIPC expresses high level of AR and nuclear receptor(NR) coactivators, such as TIF-2, ARA24, PIAS, SRC-1.
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