目的研制低分子肝素纳米脂质体制剂及其鼻腔吸收。
OBJECTIVE To investigate the preparation of low molecular weight heparin nanoliposomes and their nasal absorption.
方法:用超声-匀浆-冷冻干燥法制备丹参酮IIA纳米脂质体。
METHODS Tanshinone IIA nano-liposomes were prepared by ultrasonic bath-refining lyophilization method.
目的研究尼莫地平纳米脂质体冻干粉的性质,建立其质量评价方法。
OBJECTIVE to study the properties of nimodipine nanoliposomes and to establish the quality evaluation methods.
目的研究辛夷挥发油纳米脂质体滴鼻剂对儿童变应性鼻炎的临床疗效。
Objective To observe the clinical efficacy of Flos Magnoliae volatile oil nano-liposome nasal drops (FMO) in treating pediatric allergic rhinitis (PAR).
分别采用冻融法、逆相蒸发法、超声-匀浆-冷冻干燥法制备丹参酮IIA纳米脂质体。
Methods: TotanshinoneIIA Nano-liposomes were prepared by freeze-melt, reverse phase evaporation and ultrasonic bath-refining-freeze-drying.
结论上述方法适用于尼莫地平纳米脂质体冻干粉的质量评价,可有效地反映其各方面的性质。
CONCLUSION Hie methods above were suitable for the quality evaluation of nimodipine nanoliposomes freeze-dried powder, and can effectively demonstrate its properties.
结论:原花青素柔性纳米脂质体中有效成分能较快渗透进入皮肤,并在皮肤局部较长时间蓄积。
Conclusion: the active ingredients of proanthocyanidins flexible nanoliposomes can permeate through the skin effectively and lie long time.
本文综述了纳米脂质体的制备方法、质量控制和应用等方面的研究新进展,并对前景进行了展望。
This article summarizes the latest studies of nanoliposomes on progress of the preparation method, the quality control and application, as well as the prospect of future.
采用薄膜分散与探头超声相结合的方法制备砂仁挥发油纳米脂质体,并对其形貌、大小进行了分析。
Film dispersion together with a probe supersonic method were used to prepare nano-liposomes containing volatile oil extracted from villous amomum fruits.
结论:用薄膜-超声法制成大黄素磁性纳米脂质体简便易行,大黄素的包封率仍有待进一步的提高。
Conclusion: It is easy and feasible to use membrane-ultrasound method to make the magnetic nanometer liposome of emodin, and the envelopment rate of emodin is to be further enhanced.
文中以蛋黄磷脂为主要壁材,采用乙醇注入-超声法制得稳定性较好的辅酶Q _(10)纳米脂质体。
In this study, ethanol injection-sonication method was selected to prepare stable CoQ_ (10) nano - liposomes.
结果HCPT包衣纳米脂质体给药组的瘤重抑制率及肿瘤坏死范围均显著高于其他几种制剂给药组(P<0.05)。
RESULTS The two evaluating indices of the CS-Cl-coated HCPT nanoliposomes were both significantly higher than those of the other four groups(P<0.05).
结果HCPT包衣纳米脂质体给药组的瘤重抑制率及肿瘤坏死范围均显著高于其他几种制剂给药组(P<0.05)。
RESULTS The two evaluating indices of the CS-Cl-coated HCPT nanoliposomes were both significantly higher than those of the other four groups(P<0.05).
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