目的探讨肿瘤细胞表面dr5表达水平与其对肿瘤坏死因子相关的凋亡诱导配体(TRAIL)敏感性之间的关系。
Objective to investigate the correlation between sensitivity to tumor necrosis factor-related apoptosis inducing ligand (TRAIL) and expression level of death receptor 5 (DR5) on tumor cell surface.
目的探讨小儿皮肤血管瘤各阶段肿瘤坏死因子相关凋亡诱导配体(TRAIL)的表达与细胞增殖和凋亡的关系。
Aim: to investigate the relationship between the expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), cell proliferation and apoptosis in children's skin hemangioma.
目的:探讨肿瘤坏死因子相关凋亡诱导配体(TRAIL)联合化疗药物治疗神经母细胞瘤(NB)的作用及其可能机制。
Objective: To explore the role of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL) combined with chemotherapeutic agents in treating neuroblastoma(NB) and the possible mechanism.
肿瘤坏死因子相关的凋亡诱导配体(TRAIL)能选择性诱导肿瘤细胞凋亡。
TNF related apoptosis inducing ligand (TRAIL) can induce specific apoptosis of cancer cells.
目的探讨脂多糖(LPS)、巨噬细胞表达肿瘤坏死因子相关凋亡诱导配体(TRAIL)和肝细胞凋亡的相互关系。
Objective to investigate the influence of lipopolysaccharide (LPS) on macrophages expressing TNF-alpha related apoptosis induced-ligand (TRAIL) and its relation to apoptosis of HepG2 cell line.
目的:探讨肿瘤坏死因子相关细胞凋亡诱导配体(TRAIL)对人卵巢癌细胞株体外生长抑制作用。
Objective: the study is to find out the inhibition action of TNF-related apoptosis-inducing ligand or APO-2ligand (TRAIL) on ovarian carcinoma cell line cultured in vitro.
目的:探讨肿瘤坏死因子相关诱导凋亡配体(trail)蛋白和顺铂协同抑制横纹肌肉瘤细胞生长和诱导凋亡作用及其机制。
AIM: to study the synergistic induction of apoptosis by TRAIL and cisplatin in rhabdomyosarcoma cells and investigate the role of mitochondrial membrane potential and caspase-3 in this process.
背景与目的:肿瘤坏死因子相关凋亡诱导配体(tumornecrosisfactor-relatedapoptosisinducingligand,TRAIL)有广谱的抗瘤作用,且对正常组织细胞无毒性,因此有望应用于肿瘤基因治疗。
BACKGROUND & OBJECTIVE: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells.
背景与目的:肿瘤坏死因子相关凋亡诱导配体(tumornecrosisfactor-relatedapoptosisinducingligand,TRAIL)有广谱的抗瘤作用,且对正常组织细胞无毒性,因此有望应用于肿瘤基因治疗。
BACKGROUND & OBJECTIVE: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells.
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