目的:评价复方结合雌激素片的主要药效学作用。
Objective: To evaluate the pharmacodynamics function of compound conjugated estrogen tablets.
目的了解结合雌激素倍美力对去势雌性大鼠的骨量和血脂的影响。
Purpose to determine the influence of conjugated estrogen on the bone mass and lipoprotein metabolism in ovariectomized rats.
结论:复方结合雌激素片具有明显的雌激素活性及一定的孕激素活性。
Conclusion: the compound conjugated estrogens tablets possess the estrogenic and progestational activities.
目的观察雌二醇、结合雌激素和雌激素受体调节剂对去卵巢大鼠摄食行为的影响。
ObjectiveTo investigate the effects of the estradiol, conjugated estrogen and raloxifene on the food intake behavior, locomotor activity and sucrose choice in the ovariectomized rats.
不幸的是,这和另外一个过多摄入脂肪的影响就结合起来,过多摄入脂肪通过那些储存脂肪的细胞会刺激雌激素的产生。
That, unfortunately, combines with another effect of too much fat, which is that it stimulates the production of oestrogen by cells that are involved in the storage of fat.
当它与其它组织如生殖系统组织中的雌激素受体结合时,对与生殖相关的功能没有影响。
When it binds to estrogen receptors in other tissues, such as reproductive tissues, it has no effect on their reproduction-related functions.
雌激素与血管内的受体结合通常可使血管壁保持弹性和处于扩张状态,并与其它心脏保护机制一同修复受损的脉管系统。
The normal result of this estrogen binding is that blood vessel walls remain elastic and dilated, and damage to the vasculature is repaired, among other heart-protective effects.
研究人员发现在啮齿类动物中有一种被称为27-羟基胆甾醇或27HC的小分子,它可与心脏血管内的雌激素受体结合。
The researchers found that in rodents, a molecule called 27-hydroxycholesterol, or 27HC, binds to the same receptors in the blood vessels of the heart to which estrogen binds.
目的:通过建立大鼠骨质疏松模型,研究雌激素替代治疗对骨质疏松时牙种植体骨结合的影响。
Objective: To investigate the effect of estrogen replacement therapy on osseointegration of titanium implants in ovariectomized rats.
几十年来,女性一直被告知雌激素结合孕激素服用,不仅能缓解更年期阵发性发热感、失眠症,而且能帮助保持骨骼强度、心智锐敏,而最重要的是有益心脏健康。
Women had been told for decades that estrogen taken with progestin would not only ease hot flashes and insomnia but help preserve bone strength, mental acuity and, most important, heart health.
雌激素通过与其受体(ER)结合以及与雌激素本身代谢产物毒性两条途径参与乳腺癌的发生。
There is evidence that estrogens through estrogen receptor (er) signaling pathways and estrogen metabolic products participate in the development and progression of breast cancer.
结论雌激素替代治疗结合一定频率和幅度的振动运动,可使低切变率下的全血粘度值明显降低。
Conclusion it was shown that blood viscosity at low shear rates can be decreased by certain intensity vibrating movement in ovariectomized rats with appropriate estradiol valerate replacement therapy.
在松质骨区,雌激素组和假手术组结合骨板较厚,种植体周围骨小梁及种植体与骨组织的接触均多于卵巢切除组。
In cancellous bone area, the interface bone lamella was thin, the density of trabecular bone and contact of new bone with implants were less in ovariectomized group compared with other two groups.
视神经节存在的ER免疫阳性细胞可以为雌激素提供结合位点。
ER-immunoreactive neurons in optic ganglia might provide the binding sites for estrogen and accept the feedback regulation of estrogen.
雌激素受体向耳朵一样作用于乳腺癌细胞。雌激素与受体结合,将信号输送至细胞内,使细胞呈倍数生长。
Estrogen receptors act like ears on a breast cancer cell? Estrogen attaches to the receptor and transmits signals that tells the cell to grow and multiply.
有研究表明,这类物质进入人体后可以与雌激素受体结合,影响内分泌,和乳腺癌有关。
Previously published studies have shown that parabens are able to be absorbed through the skin and to bind to the body's estrogen-receptors, where they can encourage breast cancer cell growth.
因此,推荐将鼠肝癌细胞代谢活化与重组基因酵母检测的方法相结合,用于环境样品中直接和间接雌激素效应物质的检测。
Therefore it is recommended to combine the yeast assay with the metabolic activation method based on H4IIE cell line to assay the direct and indirect estrogenic chemicals in environmental samples.
因此,推荐将鼠肝癌细胞代谢活化与重组基因酵母检测的方法相结合,用于环境样品中直接和间接雌激素效应物质的检测。
Therefore it is recommended to combine the yeast assay with the metabolic activation method based on H4IIE cell line to assay the direct and indirect estrogenic chemicals in environmental samples.
应用推荐