血管内皮细胞生长因子(VEGF)及其受体在肿瘤血管新生中起重要作用，阻断VEGF的生成已成为抗肿瘤治疗的新靶点。
Vascular endothelial growth factor (VEGF) and its receptor play a critical role in tumor-associated angiogenesis and have become the new targets of anti-tumor therapy.
血管内皮细胞生长因子及其受体在肿瘤新生血管形成中起重要作用，成为肿瘤治疗的新靶点。
Vascular endothelial growth factor (VEGF) and its receptor play a critical role in tumor associated angiogenesis and has become the new targets of anti tumor therapy.
贝伐单抗通过抑制被称为血管内皮生长因子的蛋白，来抑制肿瘤组织的新生血管的生长。
Bevacizumab blocks a protein called vascular endothelial growth factor, thus inhibiting the production of new blood vessels around tumors.
新生血管大量形成在实体瘤的生长和转移中起着关键的作用。血管内皮生长因子(VEGF)是介导肿瘤血管生成的最主要因素。
New vessel formation plays a key role in tumor growth and transforming, and the Vascular endothelial growth factor (VEGF) is the most important factor inducing tumor vessel formation.
目的探讨水蛭素活性因子对S180肿瘤及血管新生的影响，为临床用药提供理论依据。
ObjectiveTo explore the effect of hirudin active factor on S180 tumor and angiogenesis so as to provide the theoretical basis for clinical medication.
肿瘤细胞释放可溶性的促血管生成因子诱导新生血管生成。
Tumor cells release soluble angiogenic factors inducing neovascularization, a process referred to as the "angiogenic switch".
血管内皮生长因子- C (VEGF - C)和血管内皮生长因子d (VEGF - D)可以诱导肿瘤新生淋巴管形成，并促进肿瘤淋巴道转移。
Vascular endothelial growth factors such as VEGF-C and VEGF-D can induce the growth of tumor lymphatic vessels and promote tumor metastasis through the lymphatic system.
血管生成促进因子和血管生成抑制因子的平衡控制着肿瘤新生血管的形成。
Formation of tumor new vessels is controlled by balances between angiogenic stimulators and inhibitors.
内皮抑素是一种抗血管生成的抑制因子，它特异性地作用于新生微血管的内皮细胞，其水平与肿瘤血管生成有着明显的相关性。
Endostatin is a kind of angiogenesis inhibitor, specific effecting in the new microvascular endothelial cells. The level of endostatin and the angiogenesis of tumor have a close correlation.
结论实验表明，水蛭素活性因子对S180肿瘤和CAM新生血管具有较强的抑制作用。
ConclusionThe experiments show that hirudin active factors have strong inhibition effect on S180 Tumor and CAM angiogenesis.
肿瘤的生长和转移依赖于新生血管的形成，血管内皮生长因子（VEGF）在肿瘤新生血管形成中起关键作用。
Tumor growth and metastasis largely depend on angiogenesis and the vascular endothelial growth factor(VEGF) play a critical rule in tumor-associated angiogenesis.
肿瘤的生长和转移依赖于新生血管的形成，血管内皮生长因子（VEGF）在肿瘤新生血管形成中起关键作用。
Tumor growth and metastasis largely depend on angiogenesis and the vascular endothelial growth factor(VEGF) play a critical rule in tumor-associated angiogenesis.
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