极光激酶A(AIK)是一种调节细胞周期的丝氨酸/苏氨酸蛋白激酶,在多种肿瘤细胞系中过表达(1-3)。
Aurora A (AIK) is a cell cycle-regulated serine/threonine protein kinase that is overexpressed in many tumor cell lines (1-3).
cdc2蛋白激酶的激活参与调节真核细胞进入有丝分裂,cdc2的激活受多个步骤的调控,包括周期蛋白的结合、cdc2苏氨酸161位的磷酸化(1)。
The entry of eukaryotic cells into mitosis is regulated by cdc2 kinase activation, a process controlled at several steps including cyclin binding and phosphorylation of cdc2 at Thr161 (1).
cdc2蛋白激酶的激活参与调节真核细胞进入有丝分裂,cdc2的激活受多个步骤的调控,包括周期蛋白的结合、cdc2苏氨酸161位的磷酸化(1)。
The entry of eukaryotic cells into mitosis is regulated by cdc2 kinase activation, a process controlled at several steps including cyclin binding and phosphorylation of cdc2 at Thr161 (1).
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