目的探讨荧光原位杂交(FISH)技术的临床价值。
Objective To explore clinical value of the fluorescent in situ hybridization (FISH) technique.
其技术主要包括胚胎活检、聚合酶链反应及荧光原位杂交。
The basic techniques currently used involve embryo biopsy, the polymerase chain reaction and fluorescence in situ hybridization.
目的建立多色荧光原位杂交技术检测人卵细胞染色体非整倍体的方法。
Objective: To establish the method of aneuploidy detection in human oocytes by multicolor fluorescence in-situ hybridization (M-FISH).
另外，荧光原位杂交技术可以鉴别有关病理学表现的新的循环遗传改变。
In addition, the technique of hybridization in situ with fluorescence allowed him to identify new recurrent genetic changes that are involved in the appearance of this pathology.
荧光原位杂交检测原发性硬化性胆管炎：有用的检测还是随机选择的结果？
Fluorescent in situ hybridization testing in primary sclerosing cholangitis: Useful testing or a random chance result?
荧光原位杂交、DNA指纹等现代分子生物技术在废水治理过程中得到了广泛的应用。
Modern molecular biotechnology such as fluorescence in situ hybridization and DNA fingerprinting was widely applied in wastewater treatment.
着丝粒和端粒DNA探针多色荧光原位杂交是一种较为精确的分析微核染色体组成的方法。
Multicolor FISH with centormeric and telomeric DNA probes was a precise technique for analyzing chromosomal composition of MN.
端粒克隆、着丝粒克隆以及重叠群之间空缺的大小都经过粗线期染色体荧光原位杂交鉴定。
BAC clones corresponding to telomeres, as well as to the centromere position and the gap sizes between contigs, were determined by BAC-pachytene chromosome fluorescence in situ hybridization (FISH).
目的探讨一种以胎盘绒毛取样进行荧光原位杂交（FISH）快速诊断染色体数目的方法。
Objective To study the numerical abnormality of chromosomes in lung cancer by dual-color fluorescence in situ hybridization(FISH).
目的探讨用多色荧光原位杂交(MFISH)技术检测的易位和双着丝粒染色体畸变的差异。
Objective To explore the differences between radiation-induced translocation and dicentric chromosome aberrations detected by multicolor fluorescence in situ hybridization (M-FISH) method.
测定荧光原位杂交(FISH)分析法对现场未确定细胞病理学结论的患者的敏感性和特异性。
To determine the sensitivity and specificity of FISH analysis in patients with inconclusive on-site cytopathology results.
通过靶向测序和荧光原位杂交技术发现，3例均存在ZC 3h7b -BCOR基因融合。
All 3 ESS were found to harbor ZC3H7B-BCOR gene fusions by targeted sequencing and fluorescence in situ hybridization.
荧光原位杂交是当前分子细胞遗传学最重要的技术之一，克服了实体瘤经典细胞遗传学研究的主要障碍。
Florescence in situ hybridization (FISH), one of the most important molecular cytogenetic techniques, overcomes the main inconvenience in classical cytogenetic methods in solid tumors.
这5例至少局灶存在经典的组织学形态，荧光原位杂交检测DDIT3基因均出现重排，无mdm2扩增。
All 5 cases exhibited at least focal classic histologic findings. All harbored DDIT3 gene rearrangements, and none harbored MDM2 amplifications according to fluorescence in situ hybridization.
结论与传统的染色体显带技术相比，荧光原位杂交技术具有高效、灵敏、可靠的特点，可为临床提供良好的辅助诊断。
Conclusions Compared with the conventional chromosome banding technique, FISH has characteristics of high sensitivity and accuracy, and provides a good assist method for diagnosis.
粗线期染色体荧光原位杂交结果表明，大多数染色体的末端都有端粒串联重复，但信号的强度在不同染色体上是不同的。
Pachytene FISH results showed that most of chromosome ends possess the telomere tandem repeats, but the signals on different chromosomes were not the same in intensity.
目的探讨多重荧光原位杂交(M -FISH)技术检测慢性淋巴细胞白血病(CLL)复杂核型异常(CCA)的价值。
Objective To investigate the value of multiplex fluorescence in situ hybridization (M-FISH) in the detection of complex chromosomal abnormalities (CCAs) of chronic lymphocytic leukemia (CLL).
目前我们采用荧光原位杂交(FISH)分析法对胰腺肿块细针穿刺活检(FNA)样本行染色体异常检测还没有深入研究。
Detection of chromosomal abnormalities by fluorescence in situ hybridization (FISH) analysis has not been well-studied in FNA samples of pancreatic masses.
通过粗线期染色体荧光原位杂交技术，将发生易位的第6号和第12号染色体的易位点分别锚定在1个和3个BAC克隆库中。
Transpositional points between chromosome 6 and 12 were anchored in 1 and 3 BAC clone's pool respectively by fluorescence in situ hybridization technology of pachytene chromosomes.
方法联合应用常规细胞遗传学、间期荧光原位杂交技术和多重荧光原位杂交技术对14例伴有复杂核型异常的aml患者进行研究。
Methods Multiplex FISH was used in combination with conventional cytogenetics (CC) and interphase FISH to study 14 cases of AML with complex karyotypic abnormalities.
方法采用常规染色体G 带分析和荧光原位杂交（FISH）方法对155例NHL患者的淋巴结组织进行细胞和分子遗传学研究。
Methods Routine G banding chromosome analysis and fluorescent in situ hybridization(FISH)were performed on lymph node specimens from 155 NHL patients.
方法：取试管婴儿助孕技术后未能受精成功的卵细胞，采用多色荧光原位杂交方法检测卵细胞13，16 ，18，2 1和2 2号染色体的情况。
Methods:Multicolor fluorescence in situ hybridization (M-FISH) was applied to check the chromosome status in oocytes for chromome 13,16,18,21 and 22.
方法：取试管婴儿助孕技术后未能受精成功的卵细胞，采用多色荧光原位杂交方法检测卵细胞13，16 ，18，2 1和2 2号染色体的情况。
Methods:Multicolor fluorescence in situ hybridization (M-FISH) was applied to check the chromosome status in oocytes for chromome 13,16,18,21 and 22.
应用推荐