为了利用这种基质金属蛋白酶，钱博士将他的荧光染料和一些正电荷一同连接在一个小的发夹形状的蛋白质分子的一端。
To make use of the MMPs, Dr. Tsien attaches his fluorescent dye, along with some positive charges, to one side of a small hairpin-shaped protein molecule.
金属蛋白酶可逆的抑制剂，无毒。
目的探讨基质金属蛋白酶及其抑制因子与组织纤维化的关系。
Objective to discuss the relationship between matrix metalloproteinases and its tissue inhibitors and tissue fibrosis.
目的：评价基质金属蛋白酶抑制剂临床应用的疗效与安全性。
OBJECTIVE: to evaluate the efficiency and safety of matrix metallo-proteinase inhibitor in clinical application.
目的：了解金属蛋白酶组织抑制因子- 1在食管癌中的作用。
Purpose: to investigate tissue inhibitor of metalloprotEinase-1 (TIMP1) gene expression in patients with carcinoma of esophagus.
目的观察5 -脂氧合酶抑制剂对黑色素瘤细胞产生金属蛋白酶的作用。
Aim to study the effects of5 lipoxygenase inhibitors on the production of matrix metalloproteinases of melanoma cells.
有几种酶——如基质金属蛋白酶和胶原酶——可能派上用场，但矫枉过正也会有风险。
Several enzymes, such as matrix metalloproteinases and collagenases, might do the job, but overdoing it could be risky.
基质金属蛋白酶是一类结构相关的内肽酶家族，能够降解细胞外基质成分。
The matrix metalloproteinases are a family of structurally related endopeptidases, they have the ability to degrade all components of extracellular matrix.
这是一系列尤其容易被基质金属蛋白酶切断的氨基酸(蛋白质的基石)序列。
This is a sequence of amino acids (the building blocks of proteins) that is particularly vulnerable to the cutting action of MMPs.
细胞外基质是构成血管壁的主要成分，其代谢平衡受基质金属蛋白酶的调节。
Extracellular matrix is the main composition which constitute blood vessel wall, its balance of metabolism is to suffer the matrix metalloproteinases to regulate.
明胶酶谱法测量血液循环中基质金属蛋白酶- 9 (MMP - 9)水平。
Gelatin zymography was used to measure blood levels of circulating matrix metalloproteinase-9 (MMP-9).
结论：基质金属蛋白酶的高表达有助于判断宫颈癌的转移潜能并指导临床治疗。
Conclusion the positive expression of MMPs can be used to estimate the metastatic potentiality and guide the clinical treatment.
金属蛋白酶抑制剂，含有它们的药物组合物和其药物用途，其制备方法和中间体。
Inhibitors of metalloproteinase, pharmaceutical compositions containing them, their pharmaceutical application and methods and intermediate compounds for their preparation.
金属蛋白酶抑制剂，含有它们的药物组合物和其药物用途，其制备方法和中间体。
Metalloproteinase inhibitors, pharmaceutical compositions containing the same and their pharmaceutical USES, and methods and intermediates useful for their preparation.
目的探讨组织金属蛋白酶抑制剂（TIMP）在食管鳞癌中的表达及其临床意义。
Objective To investigate the expression of the tissue inhibitor of metalloproteinases (TIMP) in human esophageal squamous cell carcinoma(ESCC).
目的：探讨基质金属蛋白酶- 9 (MMP - 9)在心肌再灌注损伤中的作用。
AIM: To study the roles of matrix metalloproteinase-9 (MMP-9) in the myocardial reperfusion injury.
逆转录多聚酶链反应检测间质胶原酶及金属蛋白酶组织抑制因子- 1基因表达水平。
The gene expression levels for interstitial collagenase and tissue inhibitor of metallo-proteinase-1 (TIMP-1) were measured by reverse transcription polymerase chain reaction.
目的：探讨基质金属蛋白酶-9（MMP9）和CD147在乳腺癌中的表达及意义。
Objective:To observe the expression and its significances of MMP9 and CD147 protein in breast cancer.
目的探讨血清去整合素-金属蛋白酶8 (ADAM8)水平对肺癌诊断及预后的价值。
Objective To investigate the value of serum ADAM8 level in diagnosis and prognosis of lung cancer.
随着时间的推移，金属蛋白酶以及其他的酶类慢慢地降解主动脉壁，可能导致主动脉扩张。
Over time, matrix metalloproteinases and other enzymes slowly degrade the aortic walls, possibly leading to aortic dilation.
目的：探讨结直肠癌环氧化酶- 2和基质金属蛋白酶- 7的表达与侵袭、转移的关系。
Objective: To investigate the expression of COX-2 and MMP-7 and their influence on invasion and metastasis in colorectal cancer.
目的探讨膜型基质金属蛋白酶-1在人脑胶质瘤中的表达及其与肿瘤生物学行为和预后的关系。
Objective To investigate the expression of membrane type-1 matrix metalloproteinase(MT1-MMP) in human glioma and its relationship to clinicopathological factors and prognosis of glioma patients.
结果患者血清基质金属蛋白酶-9水平高于健康对照组，差异有显著性意义（P<0.01）；
Results The serum levels of MMP-9 in IPF were significantly higher than that of healthy control, with significant difference (P<0.01).
目的：探讨基质金属蛋白酶2 (MMP - 2)在体外构建的C6细胞侵袭模型中的作用。
Objective: To study the function of matrix metalloproteinase-2 (MMP-2) in the selected C6 cells invasion model in vitro.
感染引发早产的机制与前列腺素的合成、细胞因子的异常分泌、基质金属蛋白酶活性增加等有关。
The mechanism of premature delivery caused by infection involves in increased prostaglandin synthesis, abnormal secretion of cytokines and increased activity of matrix metalloproteinases.
目的：探讨碱性成纤维细胞生长因子对基质金属蛋白酶表达的影响及其在球囊术后再狭窄中的作用。
Objective: To investigate the effect of basic fibroblast growth factor on matrix metalloproteinases and restenosis after PTCA .
目的：观察基质金属蛋白酶- 7 (MMP - 7)蛋白在鼻咽癌中的表达及与肿瘤侵袭转移的关系。
Objective: To observe the expression of matrix metalloproteinase-7 (MMP-7) in nasopharyngeal carcinoma and it's significance in metastasis.
目的：检测肝细胞癌患者血清血管内皮生长因子与基质金属蛋白酶- 9含量并分析与临床分期的相关性。
Objective to detect the concentration of serum vascular endothelial growth factor and matrix metalloproteinase-9 in hepatocellular carcinoma and analyze their relation with the clinical stages.
目的探讨脑星形细胞瘤瘤周水肿表观扩散系数（ADC）值与基质金属蛋白酶（MMP-9）表达的关系。
Objective To discuss the correlation between MMP-9 expression levels and ADC values in peritumoral edema of cerebral astrocytoma.
目的：探讨基质金属蛋白酶10 (MMP10)基因及其蛋白在人自然流产蜕膜中的表达水平及临床意义。
Objective: To discuss expression levels of MMP10 gene and protein in human spontaneous abortion deciduas and its significance in clinic.
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