目的：研究雄激素受体(AR)的基因调控。
Objective to determine the gene regulation of androgen receptor (AR).
本发明提供一类雄激素受体靶向剂(ARTA)。
This invention provides a class of androgen receptor targeting agents (ARTA).
关键是所谓选择性雄激素受体调节剂，或行动情报处。
The key is something called a selective androgen receptor modulator, or SARM.
目的探讨雄激素受体基因CAG多态性与痤疮中医分型的相关性。
Objective to study the relativity of the CAG polymorphisms of androgen receptor gene of the patients with acne and syndrome differentiation and typing of TCM.
结构式(i)的化合物是组织选择性的雄激素受体(AR)调节剂。
Compounds of structural formula (I) are modulators of the androgen receptor (ar) in a tissue selective manner.
雄激素通过雄激素受体影响成骨细胞功能，各种局部因子起调节作用。
Androgen affects osteoblasts through androgen receptors. Various local cell factors play regulating roles.
方法应用荧光激活细胞分离器（FACS）检测雄激素受体阳性的细胞。
METHODS The percentage of androgen receptor positive cells were detected by fluorescence activated cell sorter (FACS).
摘要：本研究旨在探讨大蒜素对小鼠脾细胞雌激素和雄激素受体的影响。
Abstract: the aim of this study was to observe the effects of allicin on estrogen and androgen receptors of mice spleen cells.
对201摘录，11人已被发现，以遏止雄激素受体活性的40 %以上。
Of the 201 extracts, 11 were found to deter androgen receptor activity by more than 40%.
该试剂定义新一亚类化合物，它们是选择性雄激素受体调节剂(SARM)。
The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM).
如果，相同的补充，你可以放大你的肌肉的雄激素受体切换的能力对肌肉增长？
What if, with the same supplement, you could amplify your muscle's androgen receptors ability to switch on muscle growth?
建立以氯霉素乙酰化酶(CAT)为报告基因的雄激素受体(AR)报告基因试验。
To develop an androgen receptor (AR) reporter gene assay in which the reporter gene is chloramphenicol acetyltransferase (CAT).
没有雄激素受体对雄激素发生反应，研究者开始想到雄激素受体并非他们原来想象得那样起作用。
Without male hormone receptors to respond to testosterone, the researchers started to suspect androgen receptors were not the players they had been assumed to be.
目的探讨无精或严重少弱精症患者与雄激素受体基因（CAG）n重复多态性的关系。
Objective:To study the relationship between polymorphism of (CAG)n repeats within androgen receptor gene with severe oligozoospermia or azoospermia patients.
已发现几种SARM化合物具有意外的雄激素受体之非甾族配体的促雄性和合成代谢活性。
Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor.
目的通过人雄激素受体(HUMARA)基因位点克隆性分析技术确定掌纤维瘤病是否为肿瘤性增生。
Objective to study the clonality of palmar fibromatosis by molecular genetic analysis of X chromosome inactivation pattern at a polymorphic site of human androgen receptor gene (HUMARA).
目的探讨雄激素受体基因微卫星CAG多态性与多囊卵巢综合征（PCOS）患者高雄激素血症的关系。
Objective: To explore the relationship between CAG microsatellite polymorphism of androgen receptor gene and hyperandrogenism of polycystic ovary syndrome (PCOS).
结论MCF-7乳腺癌细胞株中雄激素受体存在自动调节，氟他胺和羟基氟他胺上调雄激素受体的表达。
CONCLUSIONS Androgen can autoregulate the expression of androgen receptor in MCF-7 breast cancer cell line. Flutamide and hydroxyflutamide up regulate the expression of androgen receptor.
研究结果提示，精索静脉曲张睾丸功能障碍可能与血清睾酮浓度低下及睾丸细胞核雄激素受体反应异常有关。
The authors suggest that the disturbed function of testes in rats with varicocele may be related to lower values of serum testosterone and abnormal reaction of NAR in testes.
目的：探讨雄激素受体(AR)和胰岛素受体(INSR)在不对称性多囊卵巢(PCO)局部发病机制中的作用。
Objective: to probe the role of androgen receptor (ar) and insulin receptor (INSR) in pathogenesis of asymmetric polycystic ovaries (PCO) as local factors.
目的：探讨人雄激素受体（AR）基因第一外显子CAG串联短重复序列（STR）多态性与肺癌发生之间的关系。
Objective:To investigate the relationship between the polymorphic CAG short-tandem repeat(STR) at the androgen receptor(AR) gene exon 1 and lung cancer.
探讨不对称性多囊卵巢(PCO)的临床特点及雄激素受体(AR)和胰岛素受体(IR)在其发病机制中的作用。
To study the clinical features and the role of androgen receptor (ar) and insulin receptor (IR) in auto-para endocrine control of asymmetric polycystic ovaries (PCO).
为了弄清ar -V7的雄激素受体区别与其他，研究者发现实验室生长的前列腺癌细胞只产生AR - V 7序列。
To see how androgen receptors made from AR-V7 differ from others, the researchers forced lab-grown prostate cancer cells to produce only the AR-V7 sequence.
雄激素受体基因突变、多种途径引起的异常磷酸化激活和共激活物的调节失控等是激素非依赖性前列腺癌形成的主要促成因素。
The mutation of androgen receptor gene, abnormal phosphorylation and abnormal regulation of co-activators contribute to the formation of androgen-independent prostate cancer.
结论中国汉族雄激素受体基因微卫星CAG多态性对PCOS高雄激素血症的形成无明显关系，不是PCOS的主要致病因素。
Conclusion: androgen receptor gene CAG microsatellite polymorphism exists in Chinese women does not significantly relate with pathogenesis of hyperandrogenism and is not the main cause of PCOS.
方法：采用放射配体方法测定实验组（A组）与对照组（B组）外周血雄激素受体（AR）水平及痤疮患者服药后AR水平。
Method:Peripheral blood AR levels were measured with rodioligand assay in 13-cis retinoid acid group (group A) and in control group (group B).
目的：利用RNA干涉技术抑制雄激素受体（AR）的表达，研究AR在激素依赖性和激素非依赖性前列腺癌细胞增殖中的作用。
AIM: To study the role of androgen receptor (AR) in hormone-dependent and hormone-independent prostate cancer cell proliferation by knocking down AR expression with adenovirus-delivered siRNA.
大多数论证认为多基因会引致雄性脱发，而其中最为重要的的是雄激素受体基因，该基因位于X性染色体(对于男性来说遗传自母亲)。
Most likely there are multiple genes that contribute towards MPB, the most important of which appears to be the Androgen Receptor gene, located on the X chromosome (inherited from the mother).
目前来看，它的作用是上调前列腺素e2(一种帮助头发生长的激素)，同时能够抑制雄激素受体的相关功能，促进和保护了头发毛囊的生长。
Basically what it does is up-regulate PGE2 which AIDS in hair growth, suppresses androgen receptor related functions, promotes maintenance, and significantly improves the functions of hair follicles.
目前来看，它的作用是上调前列腺素e2(一种帮助头发生长的激素)，同时能够抑制雄激素受体的相关功能，促进和保护了头发毛囊的生长。
Basically what it does is up-regulate PGE2 which AIDS in hair growth, suppresses androgen receptor related functions, promotes maintenance, and significantly improves the functions of hair follicles.
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