目的回顾近年国内外骨骼肌成肌细胞移植的相关研究进展。
Objective To review the research progress in transplantation of the skeletal muscle myoblast.
以连续贴壁法筛选大鼠骨骼肌成肌细胞，接种于96孔板进行单克隆培养。
Rat skeletal myoblasts were selected with continuous adherence method for monoclonal cultivation by inoculating into a 96-pore plate.
这些临床前实验数据证明了骨骼肌成肌细胞疗法的可行性和安全性，为初期人体试验的进行铺平了道路。
These preclinical data have paved the way for the early human trials which have confirmed the feasibility and safety of this approach.
近年来，应用骨骼肌成肌细胞心肌内移植替代损伤心肌及疤痕组织的研究取得了很大进展，受到广泛关注。
Recently, the research on applying skeletal muscle myoblast to transplant within the myocardium to replace the damaged myocardium and scar tissue developed greatly and are widely paid attention to.
目的：总结成肌细胞在骨骼肌收缩功能和细胞基因治疗研究中的应用。
OBJECTIVE: To summarize the application of myoblast in skeletal muscle contraction and gene treatment research.
对该基因表达的抑制可引起成肌细胞的过度增殖和肌纤维的肥大，从而引起骨骼肌增生。
The inhibition of Myostatin expression can accelerate the myoblast proliferation and myofibril hypertrophy, which results in the skeletal muscle hyperplasia.
纳入标准：有关成肌细胞的生物学特性、在骨骼肌收缩中的应用、在基因治疗中应用方面的文献。
Inclusive criteria: Literature about the biological characteristics of myoblast, the application in skeletal muscle contraction and gene treatment.
结论：成肌细胞可以为骨骼肌在收缩功能上的研究提供一个很好的研究平台，其在基因治疗研究中的应用也为肌组织工程的研究奠定了基础。
CONCLUSION: Myoblast provides a research platform for skeletal muscle contraction function, which also lays a foundation for the muscle tissue engineering research in gene treatment.
目的观察慢性压迫性脊髓损伤后骨骼肌形态学改变及其成肌细胞的增殖动力学变化。
Objective To observe the morphological changes and myoblast proliferation dynamics of skeletal muscle after chronic spinal cord compression in rats.
制备成肌细胞的初级培养物，可以将10-30天的大鼠胚胎骨骼肌组织剪切下来。
A primary culture of myoblasts may be prepared by excising skeletal muscle tissue from 10 to 30 day old rat embryos.
目的：探讨香烟烟雾浓缩物(CSC)对小鼠骨骼肌c2c 12成肌细胞分化的影响。
AIM: To study the effect of cigarette smoking condensate (CSC) on myogenic differentiation of murine skeletal muscle C2C12 cells.
目的：探讨香烟烟雾浓缩物(CSC)对小鼠骨骼肌c2c 12成肌细胞分化的影响。
AIM: To study the effect of cigarette smoking condensate (CSC) on myogenic differentiation of murine skeletal muscle C2C12 cells.
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