Here's a video that animates the acetylation of histone proteins in the regulation of gene expression in cancer cells.
下面的视频是关于在癌症细胞里的常规基因表达是如何进行组蛋白乙酰化作用(acetylation of histone)的。
The acetylation of histone is related to gene expression and regulation, which takes part in the pathological courses of all kinds of lung diseases.
组蛋白乙酰化修饰与基因的表达调控相关,参与了各种肺部疾病的病变过程。
The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other, which are histone transacetylase and histone deacetylase.
组蛋白乙酰化和去乙酰化由一对功能相互拮抗的蛋白酶——组蛋白乙酰基转移酶和组蛋白去乙酰化酶负责。
Studies had shown that acetylation and deacetylation of histone are of certain value on t, B cell's development, differentiation, maturation, secretion and surface factor's expression etc.
研究表明,组蛋白的乙酰化与去乙酰化状态,可作用于T、B细胞的发育、分化、成熟、分泌及表面因子的表达等多个方面。
As in the Alzheimer's mice, drugs that boosted histone acetylation improved the older mice's performance on tests of rodent cognition.
如同阿尔茨海默病鼠,增强组蛋白乙酰化的药物改善了年老小鼠在认知测试中的表现。
Combined with the results of histone deactylase inhibitor, it is suggested that histone acetylation plays an important role in hsp gene transcription regulation.
结合以上去乙酞化酶抑制剂的实验结果,我们认为组蛋白乙酞化修饰参与了热休克基因的表达调控。
This review focuses on how aberrant covalent histone modifications such as acetylation and methylation may contribute to the development of alimentary canal neoplasms.
主要探讨组蛋白共价修饰中乙酰化和甲基化在消化道肿瘤形成过程中的作用。
The level of his-tone acetylation is determined by the activities of histone acetyltransferases and histone deacetylases.
组蛋白乙酰转移酶和组蛋白去乙酰酶活性共同决定了组蛋白的乙酰化水平。
Histone deacetylase inhibitors increase the acetylation level of histone as well as some non-histone proteins, and specifically modulate some gene expression.
组蛋白去乙酰酶抑制剂可提高组蛋白的乙酰化水平,并对一些非组蛋白成分产生影响,从而调节某些特定基因的表达。
Purpose to investigate the effects of DNA methylation and histone acetylation on the expression of tumor associated genes and cell cycle progression in human colonic cancer cells.
目的观察dna甲基化和组蛋白乙酰化对人结肠癌细胞系癌相关基因的表达和细胞周期的影响。
Histone acetylation contributes to expression of gene, while histone deacetylation leads to repression of gene expression.
组蛋白乙酰化促进基因表达,而去乙酰化则抑制基因表达。
In the 10 May 2007 issue of Nature, they reported that a drug that promotes histone acetylation improved learning and memory in a mouse model of Alzheimer's disease.
在2007年5月10日的自然杂志中,他们报道了一种促进组蛋白乙酰化的药物,它能增强阿耳茨海默氏病模型老鼠的学习和记忆能力。
Histone acetylation and de-acetylation can change the structure of chromatin, involving in gene expression regulation and nuclear reprogramming.
组蛋白乙酰化和去乙酰化可以改变染色质的结构,参与基因的表达调控和重编程。
HDAC and histone deacetylase inhibitors (HDI) can affect expression of some specific genes and induce cell differentiation growth arrest and apoptosis through regulating histone acetylation level.
组蛋白脱乙酰基酶与组蛋白脱乙酰基酶抑制剂通过对组蛋白乙酰化水平的调控,影响特定基因的表达,改变细胞周期的进程。
Conclusion APP expression on SH-SY5Y cells may increase through up-regulation of histone acetylation through P38MAPK pathway.
结论P 38 MAPK信号通路可能通过上调组蛋白乙酰化水平增加SH - SY5Y的APP蛋白表达。
Conclusion APP expression on SH-SY5Y cells may increase through up-regulation of histone acetylation through P38MAPK pathway.
结论P 38 MAPK信号通路可能通过上调组蛋白乙酰化水平增加SH - SY5Y的APP蛋白表达。
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