Establish a method for the determination of quinapril and its active metabolite quinaprilat in human plasma.
建立一种方法测定人血浆中喹那普利及其代谢产物喹那普利拉的浓度。
Dihydroartemisinin is the main active metabolite of artemisinin derivatives.
青蒿素衍生物的主要活性代谢产物是二氢青蒿素。
Isosorbide mononitrate is an active metabolite of isosorbide dinitrate and exerts qualitatively similar effects.
酯的一种活性分解物，并表现出同样相似的作用。
Cigarette smoking induces CYP1A2 and may, therefore, enhance the conversion of clopidogrel to its active metabolite.
吸烟诱导CYP1A2而且可能因此增强氯吡格雷转化为其活性代谢产物。
The new type of antihistamine, fexofenadine, an active metabolite of tefanadine, was introduced with its pharmacology and clinical application.
介绍了新型抗组胺药非索非那定的药理作用及临床应用。
Objective: To establish an HPLC method to determine the plasma concentrations of buspirone hydro-chloride (BuHCl) and its active metabolite 1 - pyrimidinyl - piperazine(1 - PP).
目的：建立高效液相色谱法测定血浆中盐酸丁螺环酮及其活性代谢物1-嘧啶哌嗪浓度的方法。
OBJECTIVE: To compare the antihistamine activity of desloratadine, the active metabolite of loratadine, with that of cetirizine in the skin wheal-and-flare responses during 24 hours.
目的：比较地氯雷他定(氯雷他定的活性代谢产物)与西替立嗪在24小时内对皮肤风团及潮红应答的治疗效果。
For drugs with an active metabolite, the therapeutic consequence of first-pass metabolism depends on the contributions of the drug and the metabolite to the desired and undesired effects.
对于那些生成活性代谢物的药物来讲，经过首过代谢的治疗上的重要性取决于药物和代谢物所引起的期望的和非期望的效应。
Objective:To establish a SPE-HPLC method for the determination of quinapril and its active metabolite quinaprilat in human plasma and to evaluate their pharmacokinetics and relative bioavailability.
目的：建立SPE—HPLC法测定人血浆中喹那普利及其代谢产物喹那普利拉的浓度，以研究喹那普利及喹那普利拉在健康志愿者中的药代动力学和相对生物利用度。
Conclusion There is the change of nervures system during early period of Fluoride. It is an active significant that measuring the ca metabolite can make an early diagnosis...
结论氟中毒初期就有神经系统改变，尿中儿茶酚胺酸性代谢物的测定对氟骨症早期诊断及治疗有积极的意义。
Conclusion There is the change of nervures system during early period of Fluoride. It is an active significant that measuring the ca metabolite can make an early diagnosis...
结论氟中毒初期就有神经系统改变，尿中儿茶酚胺酸性代谢物的测定对氟骨症早期诊断及治疗有积极的意义。
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