Covalent catalysis involves the substrate forming a transient covalent bond with residues in the active site or with a cofactor.
共价催化涉及底物与活性位点中的残基或与辅因子形成瞬时共价键。
You should check site statistics at least monthly if you have an active site.
如果你有一个活跃的站点，你至少应该每月都查看一下站点的统计表。
Blocks the action of target enzymes by binding nearly irreversibly to their active site.
与附近目标酶的活性位点不可逆的结合。
Preferably, the ligand does not bind to the active site of an endogenous target compound.
优选所述配体不结合内源靶化合物的活性部位。
A mechanism in which the active site of the enzyme does not change shape during catalysis.
一种在催化反应中酶活性位点形状不发生改变的机理。
The probably active site of the cross coupling reaction over nano Ni catalyst is investigated.
讨论了纳米镍催化偶联反应的可能活性位。
Mixed inhibitors distort the active site, interfering with the chemistry performed by the enzyme.
混合抑制剂扭曲了活动现场，干扰酶进行化学。
Location of the active site and relative differences in ti ue distribution can also be important.
起效部位的位置和组织分布的相对差异性也可能很重要。
Location of the active site and relative differences in tissue distribution can also be important.
起效部位的位置和组织分布的相对差异性也可能很重要。
They also designed specific inhibitors (small molecules) which bind to the active site of human DDAH.
他们也设计了一个特殊的抑制物(小分子)，它可以结合在人类DDAH的活性位点上。
It's a very active site and the 13 year old mentor I chatted with in testing the service was very well spoken.
该网站十分活跃，笔者曾和一个13岁的导师聊天。
Catalytic active site by the group and the combined group, who co-polymer with a three-dimensional structure.
活性中心由催化基团和结合基团，他们与高分子共同构成一个立体结构。
Irreversibly inhibits serine proteases by sulfonylation of the serine residue in the active site of the protease.
通过蛋白酶活性位点丝氨酸残基的磺酰化，不可逆的抑制丝氨酸蛋白酶。
So it was important from both practical and theoretical point of view to study the active site structure of prolidase.
研究脯氨肽酶活性中心的结构具有重要理论意义和潜在实用价值。
Objective: The main aim was to discuss the pain-relieving effects of active site of Psammosilene Tunicoides root (PTR).
目的：探讨金铁锁的镇痛作用及镇痛活性部位。
For instance, they might construct a compound that inhibits the active site of an enzyme crucial to viral reproduction.
举例来说，他们可以设计某个化合物，作用在病毒复制时不可或缺的酵素活性区，而加以抑制。
The feature of electronic structure and active site in these compounds were investigated on the basis of calculated results.
据此研究了它们的电子结构特征，确定了它们的活性部位。
MMOH is the active site of MMO, its catalysis reaction mechanism mainly includes the activation of alkyl and oxygen molecule.
羟基化酶是其催化活性中心，它的催化机理的研究主要包括烷烃的活化和分子氧的活化这两个方面。
OBJECTIVE To ascertain the main active site of Pollen Typhae, Pollen Typhae Carbonisatus and Pollen Typhae Parch in effect of hemostasia.
目的确定生蒲黄、炒蒲黄、蒲黄炭止血作用主要活性部位。
Basic single-chain polypeptide that inhibits numerous serine proteases by binding to the active site of the enzyme, forming tight complexes.
基本的单链多肽，通过与酶的活性位点紧密结合形成复合物，抑制大多数的丝氨酸蛋白酶。
Herein, a series of diiron dithiolate complexes were synthesized as the structural and functional models of the Fe-only hydrogenase active site.
本论文主要合成了一系列唯铁氢化酶活性中心六羰基二铁二硫模型配合物并考察其结构特性。
The lack of the sugar moiety could cause changes in the structure of the active site of the enzyme resulting in the observed modifications of the KMs.
去除糖基会使葡萄糖氧化酵素的活化位构造改变， 因而产生所观察到的KM值变化。
Oxo bridged polynuclear iron complex which serve as model compounds for the active site in metallic protein and enzymes has been studied for many years.
氧桥多核铁配合物作为一些金属蛋白和金属酶的模型化合物，得到了广泛的研究。
Irreversible inhibitor of Thrombin and other serine proteases. Inhibits by acylation of the active site of the enzyme. Much less toxic than PMSF and DFP.
凝血酶及其他丝氨酸蛋白酶的不可逆抑制剂，将活性位点酰基化。比PMSF和DF P毒性小得多。
After activation of the surface of carbon fibers, several of functional groups growth on carbon fibers, and they provide the active site for photocatalyst.
经过表面活化的碳纤维作为催化剂载体，这些表面官能团为催化剂在碳纤维上的生长提供活性位点。
The inhibitor-distorted active site has trouble converting the substrate to product before it dissociates, resulting in a lowered apparent substrate binding affinity.
扭曲抑 制剂活性部位有问题之前，它离解，导致明显的底物结合的亲和力降低转换基板产品。
By the competition plotting with mixed-substrates, it was indicated that glycolate-oxidizing activity and glycerate-oxidizing activity of GO Shared the same active site.
进一步通过两底物竞争作图表明：菠菜叶片GO氧化甘油酸反应和氧化乙醇酸反应为同一活性中心所催化。
Studies have shown that protease molecule with two non-active site binding groove (allosteric site), can be used to develop drug resistance against HIV, the new strategy.
但这是一个开始，佩里曼表示，这一研究结果为开发新型的抗艾滋病药物奠定了结构基础。
Some irreversible inhibitors even become covalently bound to amino acids in the active site of the enzyme as they are brought through the early chemical steps of catalysis.
一些不可逆抑制剂，甚至成为共价结合的酶的活性部位的氨基酸，因为他们带来的是通过早期的催化化学步骤。
Some irreversible inhibitors even become covalently bound to amino acids in the active site of the enzyme as they are brought through the early chemical steps of catalysis.
一些不可逆抑制剂，甚至成为共价结合的酶的活性部位的氨基酸，因为他们带来的是通过早期的催化化学步骤。
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