Established the IL-2 gene recombinant adenovirus vector.
人IL-2基因腺病毒载体的构建和包装。
Objective to construct recombinant adenovirus vector carrying human TRADD gene.
目的构建含有人TRADD基因片段的重组腺病毒载体。
Virus without anti-Smad was served as negative control, and that without adenovirus vector was served as blank control.
以空载病毒作为阴性对照组,以无病毒载体作为空白对照组。
Objective to construct and express a recombinant adenovirus vector which can regulate expression of human tumor suppressor gene PTEN.
目的体外构建和表达可调控性人抑癌基因pten重组腺病毒。
Adenovirus vector is an earlier and maturer genetic carrier in the respect of gene therapy and genetic immunization after retroviral vector.
腺病毒载体是继逆转录病毒载体后在基因治疗、基因免疫等方面应用开发得较早且较成熟的一种基因载体。
MDR1 gene was transfered to cord blood nucleate cells (CBNC) mediated by adenovirus vector, for enhancing its resistance to chemotherapeutic drugs.
通过腺病毒载体介导使多药耐药基因转染入脐血有核细胞,提高其对化疗药物的耐受性。
Results Fiber-mutant adenovirus vector showed a notably enhanced gene expression in four different tumor cells compared with that of conventional ones.
结果:与野生型腺病毒相比,重组腺病毒能显著地提高目的基因在四种不同肿瘤细胞中的表达。
AIM: to construct a recombinant adenovirus vector carrying AFP promoter to specifically express a targeting gene in hepatocellular carcinoma HepG2 cells.
目的:建立一种在甲胎蛋白(afp)阳性的肝癌细胞中靶向表达目的基因的重组腺病毒载体。
The failure of the Merck vaccine up on behalf of the non-replicating adenovirus vector vaccine failure, not on behalf of other AIDS vaccines will be no hope.
默克疫苗的失败至多代表非复制型腺病毒载体疫苗的失败,决不代表其他艾滋病疫苗就没有希望。
The selection and cloning of early and late promoters and removal of adenovirus terminal protein (TP) are very important in construction of adenovirus vector.
在腺病毒载体的构建过程中,早期和晚期启动子的选择、构建以及去除末端蛋白(TP)、克隆末端序列是至关重要的。
Objective: To construct a replication-competent adenovirus vector carrying human endostatin gene, looking for an effective method for the therapy of colon cancer.
目的:构建携带内皮抑素基因的增殖型腺病毒载体,寻找结肠癌的有效治疗方法。
Objective To investigate the suppression effects of a adenovirus vector containing angiostatin K1-5 gene to the proliferation and migration of vascular endothelial cells.
目的研究携带血管抑素K1-5基因的腺病毒载体对其对血管内皮细胞增殖的抑制作用。
At present, the mainly applied virus vectors are retroviral vector, adenovirus vector adenovirus-associated virus slow virus vector, herpes simplex virus vector and so on.
目前应用的病毒载体主要有逆转录病毒载体、腺病毒载体、腺病毒相关病毒、慢病毒载体、单纯疱疹病毒载体等。
Conclusion the recombinant adenovirus vector was constructed successfully by site-specific recombination technique, which provides a foundation for further research about B7-H1.
结论利用位置特性重组技术,成功的构建了人反义B7 - H1的腺病毒载体,为后续对B7 - H1的相关研究创造了条件。
Objective to construct a recombinant adenovirus vector carrying antisense heat shock protein 70 (HSP70) cDNA and observe its effect on inhibiting the growth of laryngeal carcinoma Hep-2 cells.
目的构建携带反义热休克蛋白70 (HSP70)的重组腺病毒载体以用于喉癌的基因治疗研究。
Conclusion the recombinant adenovirus vector carrying human TRADD gene was successfully constructed. It can be used for detecting the effects of TRADD on fibroblasts of hypertrophic scar and keloid.
结论构建成功的含有TRADD基因片段的重组腺病毒,可用于转染人成纤维细胞,用于检测TRADD对病理性瘢痕成纤维细胞的影响。
The hope is that modified adenovirus could play a role in gene therapy, used as a vector (carrier) for delivering therapeutic genes to the interior of cells.
人们希望,改构后的腺病毒在基因治疗方面能起到重要的作用,例如,作为载体基因携带治疗性基因到达细胞内。
Objective: to be as the foundation of the tumor therapy with targeting IL-21 gene by constructing of recombinant interleukin 21 gene adenovirus expression vector.
目的:构建含人IL -21基因的重组腺病毒表达载体,为IL - 21基因治疗肿瘤研究奠定基础。
As the newly emerging vector, recombinant adenovirus is being given more attention and has become the major vector of gene therapy because of its high rate of transfection and expression.
腺病毒作为新兴的载体因其转染效率和表达效率高而日益受到重视,成为肿瘤基因治疗的主要载体之一。
AIM: to construct the recombinant adenoviral vector carrying antisense RNA to chemokine receptors CCR5 and CXCR4 and to obtain recombinant adenovirus, which will be used to resist HIV 1 infection.
目的:构建趋化因子受体c CR 5,CXCR4双靶区反义rna重组载体并获取重组腺病毒以用于抗hiv 1基因治疗的研究。
As an important gene transfer vector, adenovirus has the deficiency of poor targeting.
腺病毒作为一种重要的基因转移载体,在应用中存在着靶向性差的问题。
Purpose To test the hypothesis that adenovirus may improve gene transfer efficiency of lentiviral vector by mediating viral entry.
目的尝试利用腺病毒介导慢病毒载体的细胞感染以提高转染效率。
The present invention discloses a recombinant canine adenovirus-2 transfer vector, a method for constructing the recombinant canine adenovirus-2 transfer vector and an applications thereof.
本发明公开了一种重组犬2型腺病毒转移载体、其构建方法及其用途。
The present invention discloses a recombinant canine adenovirus-2 transfer vector, a method for constructing the recombinant canine adenovirus-2 transfer vector and an applications thereof.
本发明公开了一种重组犬2型腺病毒转移载体、其构建方法及其用途。
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