The mutation of androgen receptor gene, abnormal phosphorylation and abnormal regulation of co-activators contribute to the formation of androgen-independent prostate cancer.
雄激素受体基因突变、多种途径引起的异常磷酸化激活和共激活物的调节失控等是激素非依赖性前列腺癌形成的主要促成因素。
It recognized even androgen-independent cancer cells, present when prostate cancer is incurable, the study by researchers at the University of Pennsylvania showed.
宾夕凡尼亚州大学的研究者说，即便是在目前来说不可治愈的非雄激素依赖性前列腺癌中也是有效的。
AIM: To study the role of androgen receptor (AR) in hormone-dependent and hormone-independent prostate cancer cell proliferation by knocking down AR expression with adenovirus-delivered siRNA.
目的：利用RNA干涉技术抑制雄激素受体（AR）的表达，研究AR在激素依赖性和激素非依赖性前列腺癌细胞增殖中的作用。
AIM: To study the role of androgen receptor (AR) in hormone-dependent and hormone-independent prostate cancer cell proliferation by knocking down AR expression with adenovirus-delivered siRNA.
目的：利用RNA干涉技术抑制雄激素受体（AR）的表达，研究AR在激素依赖性和激素非依赖性前列腺癌细胞增殖中的作用。
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