Should ACE Inhibitors be Combined with Angiotensin II Receptor Antagonists?
ACE抑制剂应与血管紧张素受体拮抗剂合用吗？
Action of a hypertensive hormone - Angiotensin II - is known to interfere with that process.
众所周知，高血压激素(血管紧缩素2)的作用干扰着这一过程。
Receptor blockers are commonly used in cardiovascular patients who have high levels of angiotensin II.
受体阻断器是针对具有高水平血管紧缩素Ⅱ的心血管疾病患者经常采用的治疗方法。
Renin is a monospecific enzyme that catalyzes the rate-limiting step in the synthesis of angiotensin II.
肾素是一种单一特异性酶，是催化血管紧张素ii合成的限速酶。
Objective: to observe the role of Angiotensin II receptor antagonist valsartan on kidney of rat with nephrotic syndrome.
前言：目的：观察血管紧张素受体拮抗剂缬沙坦对肾病综合征大鼠的干预保护作用。
Antihypertensive non-peptide angiotensin II receptor antagonists have been paid much attention since it was found in 1980's.
抗高血压新药非肽类血管紧张素ii受体拮抗剂自二十世纪八十年代发现以来就受到了广泛的关注。
Angiotensin II (Ang II) is a vasoactive peptide hormone that regulates blood pressure as well as fluid and electrolyte balance.
血管紧张素ii是心血管系统的重要活性物质，起着调节机体水、电解质平衡，维持机体正常血压等作用。
Angiotensin II is critical in both the evolution of cardiovascular complications such as myocardial infarction and eventually heart failure.
血管紧张素ii在心血管并发症(如心肌梗死、心力衰竭)的进展中起到关键作用。
This enzyme catalyses the conversion of angiotensin I to angiotensin II in the blood plasma and endothelia and prevents the breakdown of bradykinin.
这种酶催化的血管紧张素一血管紧张素血液中的血浆和内皮二，防止故障的激肽转换。
However, the value of combining spironolactone with an angiotensin II receptor blocker on LV reverse remodeling in mild-to-moderate systolic HF is unclear.
但是，对轻中度收缩性HF患者，螺内酯联合血管紧张素ii受体拮抗剂对左室(LV)逆重构的价值目前还不清楚。
Angiotensin I is then cleaved to form active angiotensin II by ACE, a zinc-containing enzyme located in the endothelial lining of the vasculature of the lungs.
然后血管紧张素i在血管紧张素转换酶作用下变为血管紧张系II，血管紧张素转换酶是一种位于肺部血管内皮的含锌酶。
ACE inhibitors work by inhibiting the conversion of angiotensin I to the potent vasoconstrictor, angiotensin II, thereby improving blood flow and blood pressure.
ACE抑制剂的工作，通过抑制血管紧张素I的转化可以强化血管，血管紧张素Ⅱ可改善血流和血压。
Following treatment with compounds to block both Angiotensin II receptors, the researchers found that by blocking one of these receptors - AT1Rs - ACE2 activity increased.
为了阻止血管紧缩素2受体而采用复合物治疗之后，研究人员发现通过阻止其中的受体之一at1rs——ACE2活动增加。
The promise of these drugs is also connected to the fact that we have begun to understand that rennin may have effects independently on the formation of angiotensin II to the traditional pathways.
之所以说这种新药很有前景还有一部分原因是，我们已经开始懂得肾素对血管紧张素ii的形成有一定的作用，且这种作用不依赖于传统的作用途径。
Angiotensin II is one of the most potent vasoconstrictors known. It is also active in the central nervous system and adrenal glands and stimulates aldosterone secretion, resulting in salt retention.
血管紧张素ii是已知的最强烈的血管收缩剂之一，它对中枢神经系统及肾上腺也有活性，能刺激肾上腺素分泌，导致钠潴留。
Angiotensin II is one of the most potent vasoconstrictors known. It is also active in the central nervous system and adrenal glands and stimulates aldosterone secretion, resulting in salt retention.
血管紧张素ii是已知的最强烈的血管收缩剂之一，它对中枢神经系统及肾上腺也有活性，能刺激肾上腺素分泌，导致钠潴留。
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