Gene targeting technology and its application in research of animal model of human disease were briefed in this paper.
本文就基因打靶技术及其在人类疾病动物模型研究中的应用做一介绍。
Animal model of human disease plays an important role in medical research, but spontaneous human disease cannot satisfy needs of medical research.
人类疾病动物模型在医学研究中起着非常重要的作用，而自然发生的人类疾病已远远不能满足医学研究的需要。
Model organisms have proven enormously valuable for studies of human disease mechanisms because regulatory pathways and physiology are so highly conserved throughout the animal kingdom.
因为整个动物王国中的生物，调节通路和生理作用是高度保守的，模型生物在人类糖尿病发病机制的研究中已被证明具有重要的价值。
We employ the nematode worm C. elegans as a model experimental system for studying the genetic mechanisms underlying the control of animal development and human disease.
作为模式生物实验系统，线虫可用于研究控制动物发育和人类疾病遗传机制。
Objective to made the animal model which is similar to the human pyelonephritis to strengthen the experimental basis for the therapy of acute urologic infectious disease.
目的制作与人肾盂肾炎相似的动物模型，为临床治疗急慢性泌尿系感染性疾病打下实验基础。
Objective to made the animal model which is similar to the human pyelonephritis to strengthen the experimental basis for the therapy of acute urologic infectious disease.
目的制作与人肾盂肾炎相似的动物模型，为临床治疗急慢性泌尿系感染性疾病打下实验基础。
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