In addition, the MVD was less significant in the anti VEGF antibody group and combination treatment group than other groups.
此外,抗vegf抗体组和两者合用组的微血管密度(MVD)明显较其他组为低。
Conclusions anti VEGF may provide a new approach to the treatment of gastric cancer by inhibiting tumor angiogenesis, and combination of anti VEGF antibody with MMC could be more effective.
结论通过抗vegf抑制血管形成,可能为胃癌的治疗提供一个新的途经,抗vegf抗体与MMC的联合使用将更为有效。
During early stage of CIA development, expression of VEGF in the joint increases and VEGF is expressed biologically active and can be inhibited by anti VEGF neutralizing antibody.
CIA形成的早期关节组织内可能产生大量的VEGF,并以较强的生物活性形式存在,能被抗vegf中和抗体抑制。
Vascular endothelial growth factor (VEGF) and its receptor play a critical role in tumor-associated angiogenesis and have become the new targets of anti-tumor therapy.
血管内皮细胞生长因子(VEGF)及其受体在肿瘤血管新生中起重要作用,阻断VEGF的生成已成为抗肿瘤治疗的新靶点。
Vascular endothelial growth factor (VEGF) and its receptor play a critical role in tumor associated angiogenesis and has become the new targets of anti tumor therapy.
血管内皮细胞生长因子及其受体在肿瘤新生血管形成中起重要作用,成为肿瘤治疗的新靶点。
Purpose To study the angiogenesis induced by OS 732 cell line and its inhibition by anti VEGF antibody.
目的:研究人骨肉瘤OS 732细胞系促血管生成作用及血管内皮生长因子(VEGF)抗体对其血管生成的抑制作用。
Objective to study the inhibiting effect of anti vascular endothelial growth factor (VEGF) on the growth and metastasis of gastric cancer.
目的研究抗血管内皮生长因子(VEGF)对胃癌生长和转移的抑制作用。
The classification, mechanism and application of VEGF and VEGFR in anti-tumor therapy are reviewed.
本文综述了VEGF及其受体的分类、作用机制及在抗肿瘤治疗中的应用。
This effect was abrogated by incubating the cells with an anti-VEGF antibody and was inhibited in the presence of gliclazide.
这种影响作用可通过将细胞培养在含抗vegf抗体中而消除,格列齐特也可抑制这种作用。
This thesis gives a review on tumor angiogenesis, the features of VEGF family, the application of VEGF on anti - tumor drugs.
本文就肿瘤血管生成、VEGF家族的特性、VEGF在抗肿瘤药物开发中的应用做一综述。
It has been a "hot spot" about VEGF in the role of the growth and development of human brain tumor and in the therapy study about anti-tumor angiogenesis.
有关VEGF在人脑肿瘤发生、演进中的作用以及抗肿瘤血管治疗的研究成为热点。
Histologic specimens were stained with anti-VEGF antibody and anti CD34 antibody.
利用免疫组化法对肿瘤标本行抗cd 34、VEGF染色。
Objective To study the effect and mechanism of anti-VEGF antibody on apoptosis of K562 cells.
目的观察抗VEGF抗体对K562细胞凋亡的影响,探讨VEGF抑制白血病细胞凋亡的机理。
Then the serum level of specific anti-VEGF antibody was detected by ELISA after 4 weeks immunization.
免疫4周后,用ELISA法检测免疫小鼠血清中特异性抗vegf抗体滴度。
The anti-VEGF antibody may be useful for the prevention and clinical treatment of the metastasis focus of osteosarcoma.
提示,VEGF抗体对骨肉瘤早期的生长有明显的抑制作用,可作为转移病灶的预防及治疗方法之一。
Methods: Based on isolation, purification and expression of VEGF, successfully prepared anti VEGF antibody and developed a sandwich radioimmunoassay for VEGF.
方法:在表达及分离纯化VEGF的基础上,成功地制备了VEGF抗体,以夹心法测定vegf。
The microvessel density and vascular endothelial growth factor was measured in surgical specimen after immunohistochemical staining using anti-factor CD34, VEGF and compared to color pixel density.
对手术标本进行抗CD34因子及抗VEGF因子免疫组化染色,测量肿块微血管密度计数及血管内皮生长因子(VEGF)阳性表达率,与超声彩色像素密度值相比较。
Methods: The different concentrations of anti VEGF antibody was used to act on SKOV3 in vitro.
方法:采用体外实验的方法将不同浓度的血管内皮生长因子抗体作用卵巢癌细胞系skov3。
Conclusion: Recombinant T7 phage vaccine expressing xenogenic VEGF can break immunologic tolerance against self-VEGF and induce the producing of specific anti-VEGF antibody.
结论:异种血管内皮生长因子基因重组T7噬菌体疫苗可打破机体对自身vegf的免疫耐受,诱导产生较高水平的特异性抗vegf抗体。
Methods The anti-VEGF antibody was connected to the surface of liposome ultrasound contrast microbubbles by the electrostatic attraction way and its physical characteristics were detected.
方法以静电吸附法将抗VEGF抗体连接到脂质体造影剂微泡的表面;
The proliferative membrane in patient with diabetic retinopathy after intravitreal injection of anti-VEGF factor is increased, and CTGF expression were higher in retinopathy proliferative membrane;
糖尿病视网膜病变患者玻璃体腔注射抗VEGF因子后视网膜增殖膜增多,CTGF在增殖膜的表达明显增加;
The proliferative membrane in patient with diabetic retinopathy after intravitreal injection of anti-VEGF factor is increased, and CTGF expression were higher in retinopathy proliferative membrane;
糖尿病视网膜病变患者玻璃体腔注射抗VEGF因子后视网膜增殖膜增多,CTGF在增殖膜的表达明显增加;
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