Antifungal drug resistance: do molecular methods provide a way forward?
抗真菌药物的耐药性：分子学方法能提供解决办法吗？
Many researches indicated that there is correlation between antifungal drug blood concentration and therapeutic effect.
另有研究也证实抗真菌药的血药浓度与其毒副作用具有相关性。
Agar dilution screening for drug susceptibility with the current panel of antifungal drugs is rapid, accurate and effective.
琼脂稀释法对于筛查当前抗真菌药物敏感性是快速、准确、有效的。
Additionally, the product is subject to the final monograph for Topical Antifungal Drug Products because its labeling contains antifungal treatment claims.
此外产品因其标签宣称具有抗真菌治疗作用，因此必须受到局部抗真菌药品法规约束。
Itraconazole, a triazole broad-spectrum antifungal drug, is notably effective on superficial and deep fungal infection, and widely used with good tolerance.
伊曲康唑为三唑类广谱抗真菌药，对浅表真菌、深部真菌感染均有显著疗效，且耐受性良好，临床应用广泛。
There are many antibacterial and antifungal drugs available, but the abuse of such drugs has generated many drug-resisting pathogens, and some bacteria even become resistant to many drugs.
目前已有多种抗细菌和抗真菌药物。但由于这些抗感染药物的滥用导致出现了众多的药物抗性致病原，有些细菌甚至出现对多种药物的抗性。
Conclusions fungal infection was caused by a rising trend year by year, attach importance to monitoring of fungal susceptibility to guide the rational selection of clinical antifungal drug.
结论真菌引起的感染呈逐年上升趋势，重视真菌药敏监测，以指导临床合理选用抗真菌药物。
For clinical reference, the new approaches in preclinical and clinical trials of voriconazole, a new triazole antifungal drug, especially results of its pharmacodynamic studies were reviewed.
介绍新一代三唑类抗真菌药活力康唑的临床前和临床研究新进展，尤其是此药的药效学研究结果，为今后临床应用提供参考。
There was a Significant difference for the mortality of pulmonary candidosis between the group of using antifungal drug after using broad spectrum antibacterial for 3 ~ 14 days and for 15 ~ 28 days.
广谱抗生素3 ~14天后使用抗真菌药物与广谱抗生素15 ~28天后使用抗真菌药物相比，可显著降低肺部真菌感染的死亡率。
Secondary objectives were incidence of infections, length of stay in hospital, time to antifungal treatment, time to first fever, and drug safety.
次要目标为感染发病率、住院时间、抗真菌治疗时间、首次发热时间和药物的安全性。
AIM:To study the antifungal effect of Xiatare(XTR, a uigur drug) and its mechanism.
目的：研究百癣夏塔热（XTR）体外抗真菌的作用，探讨其作用机理。
On the other hand, measures are being taken to accelerate development of the new antifungal agents to cope with increased drug resistance.
另一方面加快开发新的抗真菌药物，以应对日益增多的耐药真菌。
Properties of the fungicide specialized for color-deterioration transfer-coating leather were evaluated by tests of antifungal effect, physicochemical property, toxicity, smell and drug resistance.
通过杀菌效果试验，理化性质检测，毒性、刺激性试验和耐药试验，评价了自配复合型变色移膜革专用防霉剂的综合性能。
Conclusion Pay more attention to the drug resistance to the Candida isolated from the clinical. Antifungal agents should be selected reasonably according to the result of drug susceptibility test.
结论加强临床真菌分离菌株对抗菌药物耐药性的关注、根据药敏试验合理应用抗真菌药物十分重要。
Newer classes of antifungals have recently become available with broader antifungal activity, fewer drug-drug interactions, and improved tolerability when compared with the older antifungal agents.
与旧的抗真菌药物相比，目前已经问世的新型抗真菌药物拥有更广的抗菌活性、更少的药物相互作用和更好的耐受性。
OBJECTIVE to study the flora distribution and drug resistance in nosocomial infection with Candida in order to provide the reference for reasonable use of antifungal agents.
目的探讨医院假丝酵母菌属医院感染的菌种分布与耐药性，为临床合理用药提供试验依据。
Abstract Objective to investigate the characteristic of Candida infection and examine the drug resistance condition, so as to provide assistance to the reasonable use of antifungal agents clinically.
【摘要】目的探讨念珠菌感染的特点及耐药性情况，为临床合理选用抗真菌药物提供实验室依据。
Abstract Objective to investigate the characteristic of Candida infection and examine the drug resistance condition, so as to provide assistance to the reasonable use of antifungal agents clinically.
【摘要】目的探讨念珠菌感染的特点及耐药性情况，为临床合理选用抗真菌药物提供实验室依据。
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