Antisense technology is a strategy of gene therapy.
反义技术是基因治疗的一个策略。
Liver-targeted gene delivery was often seen in antisense drugs.
基因肝靶向递送多见于反义药物。
The inhibition also was antisense sequence - specific and dose - dependent.
上述抑制都是序列特异性的，与剂量呈正相关关系。
Recent advances in development and application of antisense drugs were reviewed.
本文综述了近期反义药物开发与应用的进展。
Antisense technique is an important area of research in cancer-associated treatment.
反义技术是目前癌症治疗领域很重要的一门技术。
Then, the content of melanin in antisense TRP-1 transfected melanocyte was detected.
测定TRP - 1反义核酸转染黑素细胞后细胞内黑素含量的变化。
Phase II trials with an antisense oligonucleotide against HSP-27 in CRPC are underway.
以HSP-27为靶点的反义寡核甘酸正处于第二期临床试验中。
A strategy of shotgun antisense gene silencing was used to generate a rice mutant library.
尝试利用鸟枪反义基因沉默策略构建水稻突变体库。
The protein envelope surrounding the virus was then reversed, in a process called antisense.
在一个称作反义的过程中，病毒外部的蛋白质包膜被反转。
When sense and antisense RNA molecules meet, they bind to each other and form double-stranded RNA.
当感觉和抗感觉RNA分子相遇的时候，他们结合在一起形成双链的RNA。
Conclusions: The growth of tumor can be inhibited significantly by antisense-VEGF gene transfection.
结论反义vegf基因转染可以有效地抑制喉癌的生长。
Results PCNA antisense oligodeoxynucleotides could significantly inhibit the growth of BT325 cells line.
结果PCNA反义寡核苷酸可明显抑制BT325细胞的生长；
Antisense drugs are recognized as an interesting kind of genetic therapeutics with potential wide activity.
反义药物为一种倍受关注、极具广泛活性的基因治疗药物。
Thus, it is possible to significantly suppress nonsense mutations within target genes using antisense PNAs.
由此可见，反义pna有可能在靶基因区域显著性抑制无义突变。
Objective: to screen the high performance, specific and nontoxic anti HBV antisense oligonucleotide fragment.
目的：筛选出高效特异而无毒的抗hbv反义寡核苷酸片段。
Objective To study inhibition of VEGF expression in human bladder carcinoma cells by antisense oligonucleotides.
目的观察vegf反义寡核苷酸对膀胱癌细胞VEGF表达的抑制情况。
CONCLUSION: EAAC1 antisense oligonucleotide has the neuroprotective effect against acute cerebral ischemia injury.
结论：EAAC 1反义寡核苷酸对急性脑缺血损伤有神经保护作用。
Objective to observe the effects of antisense RNA of connective tissue growth factor (CTGF) on rat liver fibrosis.
目的观察结缔组织生长因子(CTGF)反义rna对实验性肝纤维化的影响。
The first antisense RNAs' naturally occurring were identified in plasmids and other prokaryotic accessory DNA elements.
反义RNA的存在最先是在质粒和其它原核附属DNA元件中被证实的。
He tested the hypothesis by giving mice an antisense, which is a molecular compound that blocked the production of LRP.
他给小鼠服用反意物质—一种阻碍LRP表达的分子化合物—用来验证自己的猜想。
DAPI staining was used to investigate the role of HPK1 antisense oligodeoxynucleotides in hippocampus neuron death induced by OGD.
采用DAPI染色技术观察hpk1反义寡核苷酸对OGD诱导的海马神经元凋亡的作用。
Objective: To study the antisense oligonucleotide mediated inhibition on telomerase activity and cell proliferation of GBC-SD cell.
目的：探讨反义寡核苷酸对胆囊癌细胞端粒酶活性的影响及对胆囊癌细胞生长增殖的作用。
Objective To explore the efficiency of transfection of antisense oligonucleotides HA-2741 by ultrasound mediated liposome microbubbles.
目的探讨超声介导脂质体微气泡转染反义寡核苷酸ha- 2741的有效性。
Objective To evaluate the therapeutic effect of antisense oligonucleotide targeting Survivin in the treatment of tumor-bearing nude mice.
目的评价生存素反义寡核苷酸在荷肝癌小鼠中的治疗作用。
Objective to construct eukaryotic expression vector of antisense MBD1 gene fragment and to provide a tool for studying MBD1 gene function.
目的构建反义MBD1基因片段真核表达载体，为研究MBD1基因功能提供工具。
Objective: to study the effect of VEGF antisense RNA on the proliferation activity and apoptosis of human pituitary adenoma cells in vitro.
目的：研究血管内皮生长因子(VEGF)反义rna对体外培养人脑垂体瘤细胞增殖和凋亡的影响。
Objective To explore the effects of antisense proliferating cell nuclear antigen (PCNA) gene on proliferation activities of bladder cancer cells.
目的探讨反义增殖细胞核抗原(pcna)基因对膀胱癌细胞增殖活性的影响。
Objective To study the effects of antisense oligodeoxynucleotide(AS/TF) for rat tissue factor (TF) on the myocardial ischemic reperfusion injury.
目的：研究组织因子（TF）反义寡脱氧核苷酸（AS/TF）对大鼠心肌缺血再灌注损伤的作用。
Objective: To investigate the growth inhibition of antisense oligonucleotides of telomerase on liver tumor cell enhanced by albumin nanoparticles.
目的：利用纳米载体增强端粒酶反义寡核苷酸对肝脏肿瘤细胞生长的抑制作用。
Objective: To investigate the growth inhibition of antisense oligonucleotides of telomerase on liver tumor cell enhanced by albumin nanoparticles.
目的：利用纳米载体增强端粒酶反义寡核苷酸对肝脏肿瘤细胞生长的抑制作用。
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