Such small antisense RNAs may later have gained a role in RNA editing, possibly under selective pressure to repair a region or restore a reading frame after loss or erosion of a module.
之后，这些小的反义RNA可能会在RNA拼接中发挥作用，如在选择压力下修复基因组中一个区域，抑或在丧失或损坏一个模块后恢复一个读码框。
It was investigated that over-expression of P33ING1 could promote apoptosis induced by lack of serum, and transfection antisense RNA could suppress apoptosis induced by lack of serum.
有研究表明P 33ing1的过表达可促进由“血清饥饿”诱导的细胞凋亡，而转染反义rna则可抑制“血清饥饿”导致的细胞凋亡。
Also we will hear more about novel delivery techniques for drugs such as small interfering RNA and antisense DNA whose primary target organ is the liver.
此外，还有更多有关新型药物运载技术的进展，如小分子干扰rna和反义dna，其主要的靶器官是肝脏。
Objective to observe the effects of antisense RNA of connective tissue growth factor (CTGF) on rat liver fibrosis.
目的观察结缔组织生长因子(CTGF)反义rna对实验性肝纤维化的影响。
CONCLUSION CD147 antisense RNA can inhibit invasion and tumorigenesis of ovarian cancer cells and CD147 may become a new drug target of tumor therapy.
结论CD147反义核酸能抑制卵巢癌的转移和成瘤，因而有可能成为卵巢癌的治疗的药物靶点。
Objective to explore the possibility of using HBV as a gene delivery vector, and to test the anti-HBV effects by intracellular expression of antisense RNA.
目的探索利用乙型肝炎病毒(HBV)作为基因治疗载体的可能性及检验其表达反义rna抗hbv的作用。
Conclusion The recombinant adenovirus carrying antisense RNA to CCR5 has laid down a good foundation for studying its inhibiting effect on HIV-1 infection.
结论成功地构建了携带CCR5反义rna重组腺病毒载体，为研究其抗hiv 1的作用打下基础。
Results: After the transfection, antisense RNA had been successfully expressed respectively, and NK cells activity had been improved about 15%.
结果：转染后反义rna均得到高水平表达，并使NK细胞的杀伤活性提高约15%。
Antiviral activitity of the antisense RNA was evaluated by cytopathic effect using cultured IBRS2 cell and anti- IBRS2 cell infected by TGEV respectively, and the inhibitory rate was about 50%.
通过TGEV分别感染IBRS2和IBRS2抗性细胞产生的病变，结果表明该反义RNA对病毒的复制有抑制作用，其抑制率近50%。
Objective To investigate the effect of dual-target antisense RNA of hepatitis B virus (HBV) targeted to X and P region on replication and expression of HBV gene in HBV transgenic mice.
目的探讨针对乙型肝炎病毒（HBV）x、p双靶区反义RNA对乙型肝炎病毒转基因小鼠HBV复制和表达的影响。
When sense and antisense RNA molecules meet, they bind to each other and form double-stranded RNA.
当感觉和抗感觉RNA分子相遇的时候，他们结合在一起形成双链的RNA。
It was previously known that short, tiny control RNA, called antisense RNA, can stop the activity of genes by placing themselves so that "reading" of the code is impeded.
最初大家都只知道它的序列很短，是极其微小的RNA控制片断，大家叫它为反义RNA，它通过置换作用而阻止抑制基因的活性，从而阻碍密码子的转录与翻译活动。
They have been successfully used in antisense technology, for their ability to specifically bind to messenger RNA (mRNA) targets and to inhibit translation of the target genes.
由于他们能与信使核糖核酸(mRNA)靶特异性结合，进而抑制靶基因的翻译，因而在反义技术中已被成功地应用。
People utilize this characteristic of antisense RNA to adjust effectively the biological gene in the fields of animals and plants, microorganism and medicine etc. It has made the excellent success.
目前人们利用反义rna这一特点，在动植物、微生物以及医药等领域对生物基因进行有效调控，取得了令人瞩目的成就。
This paper presents the definition and action mechanism of antisense RNA; Besides, the paper reviews antisense RNA technology and its application in agricultural field.
介绍了反义rna的概念及作用机理，对反义rna技术及其在农业领域的应用进行了概述。
Objective To explore the effect of antisense RNA on hepatitis B virus (HBV) replication and antigen synthesis.
目的了解反义乙型肝炎病毒（HBV）基因转移、表达的抗HBV作用。
Objective To explore the effects of endothelin converting enzyme-1 (ECE-1) antisense RNA on ECE-1 expression in human bronchial epithelial cell line(16HBE).
目的研究内皮素转换酶-1（ECE -1）反义RNA对人气道上皮细胞ECE -1表达的抑制作用。
AIM: to construct eukaryotic antisense RNA expression vector of CD147 and probe into a new method to treat invasion and transfer of osteosarcoma.
目的：构建CD 147反义rna表达质粒载体，探索治疗骨肉瘤侵袭和转移的新方法。
Conclusion PCNA antisense RNA can significantly suppress the in vitro growth of gastric cancer cell line.
结论pcna基因反义rna对胃癌细胞的生长具有明显的抑制作用。
With the discovery of antisense RNA and further research, antisense RNA technique has been applied in the study of gene regulation.
随着反义rna的发现及对其研究的深入，反义rna技术已被广泛应用于基因调控的研究中。
Objective: to study the effect of VEGF antisense RNA on the proliferation activity and apoptosis of human pituitary adenoma cells in vitro.
目的：研究血管内皮生长因子(VEGF)反义rna对体外培养人脑垂体瘤细胞增殖和凋亡的影响。
This is binding in stand-by, you might say. But we can show that antisense RNA competes with the ribosomes to be able to attach to this stand-by site as well.
你也许会说这是具有约束力的准备，但是，我们能够证实反义RNA竞争核糖体通过预备的位点。
Objective To observe the effect of proliferating cell nuclear antigen (PCNA) antisense RNA on the growth characteristics of human gastric cancer cell.
目的观察增殖细胞核抗原(pcna)基因反义rna表达质粒对人胃癌细胞生长特性的影响，探讨其抗肿瘤作用。
Antisense RNA now being used in an attempt to provide an agent against bacteriophage genes to help in the constant struggle between lactic acid bacteria and their phages.
现在正在使用反义rna技术试图提供一种抗噬菌体遗传因子的试剂，从而帮助乳酸菌和它们的噬菌体进行长期不问断的斗争。
Results: After transfection of the antisense ERCC1, Northern and Western blotting indicated that the RNA and protein expression level of ERCC1 was obviously decreased.
结果：卵巢癌细胞转染反义ERCC1基因后，ERCC1基因转录水平、蛋白表达水平明显下降。
Conclusion Antisense ERCC1 RNA decreased the repair capability for damaged DNA in lung cancer cells induced by benzopyrene.
结论ERCC 1反义rna降低肺癌细胞对苯并(a)芘所致DNA损伤的修复能力。
AIM: to construct the recombinant adenoviral vector carrying antisense RNA to chemokine receptors CCR5 and CXCR4 and to obtain recombinant adenovirus, which will be used to resist HIV 1 infection.
目的：构建趋化因子受体c CR 5,CXCR4双靶区反义rna重组载体并获取重组腺病毒以用于抗hiv 1基因治疗的研究。
Antisense RNA exists in all kinds of living beings wildly. It ACTS on the course of the replication of DNA, transcription and translation, which realize the regulation and control of gene expression.
反义rna广泛存在于各类生物中，它作用于DNA的复制、转录、转译的过程，实现对基因表达的调控。
Conclusion Antisense telomerase RNA can block telomerase activity in SMMC7721 cells accompanied simultaneously with an increased P16 and P21 expression levels.
结论转染反义端粒酶RNA在封闭细胞端粒酶活性表达的同时，伴发P21与P16表达水平的升高。
Conclusion Antisense telomerase RNA can block telomerase activity in SMMC7721 cells accompanied simultaneously with an increased P16 and P21 expression levels.
结论转染反义端粒酶RNA在封闭细胞端粒酶活性表达的同时，伴发P21与P16表达水平的升高。
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