Depending on caspase activation, methadone overcomes doxorubicin resistance, multidrug resistance, and apoptosis resistance in leukemia cells through activation of mitochondria.
依赖于半胱氨酸蛋白酶的激活，美沙酮通过激活线粒体克服了白血病细胞中的阿霉素耐药、多药耐药、和凋亡抑制。
Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human lung cancer cell lines.
目的探讨人肺癌细胞株对化疗药物的敏感性与多药耐药相关基因和凋亡调控基因表达的关系。
In recent years, it has been realized that volume-regulated chloride channels are closely associated with proliferation, invasion, migration, apoptosis and multi drug resistance of tumor cells.
近年研究发现容积调控性氯通道与肿瘤细胞的增殖、侵袭、迁移、凋亡及多药耐药性等恶性生物学行为有关。
The drug resistance of tumor cell is related with many agents, the most important agent is that the apoptosis of tumor cell is restrained.
肿瘤细胞耐药与多方面因素有关，其中肿瘤细胞的凋亡受到抑制是一个重要的方面。
Objective: to study the induction of apoptosis and explore the mechanism of multidrug resistance of human bladder cancer.
目的：研究阿霉素诱导的细胞凋亡，探讨人膀胱癌多重抗药性机制。
Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human breast cancer cell lines.
目的探讨人乳腺癌细胞化疗敏感性与多药耐药相关基因和凋亡调控基因表达的关系。
Resistance towards apoptosis is a key factor for the survival of a malignant cell.
抗凋亡方面是一个关键因素生存的一种恶性肿瘤细胞。
Objective To study the drug resistance in different types of acute leukemia in children, the expression of multidrug resistance gene and apoptosis-related genes were analyzed.
目的通过检测儿童急性白血病多药耐药基因及细胞凋亡调控基因表达水平的改变，分析不同类型白血病的主要耐药机制。
Objective to explore the methods of inducing apoptosis in human bladder cancer multidrug resistance cells.
目的：探讨人膀胱癌多药耐药细胞凋亡诱导途径。
This is believed to be largely due to resistance of gastric adenocarcinoma cells to apoptosis induced by clinically available therapeutics.
一般认为这种情况在很大程度上是由于胃腺癌细胞对临床治疗药物诱导凋亡的抵抗。
This is believed to be largely due to resistance of gastric adenocarcinoma cells to apoptosis induced by clinically available therapeutics.
一般认为这种情况在很大程度上是由于胃腺癌细胞对临床治疗药物诱导凋亡的抵抗。
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