Methods Using the KB cell and resistant KB cell (KB/VCR) to vicristine, applying MTT assay, test drug sensitivity; PKC activity and effect of PKC modulators were studied in KB cell and KB/VCR.
方法:测定KB细胞及其耐药株的PKC活性及PKC调节剂对细胞药敏、药物代谢和耐药膜糖蛋白表达及其磷酸化的影响。
Methods Using the KB cell and resistant KB cell (KB/VCR) to vicristine, applying MTT assay, test drug sensitivity; PKC activity and effect of PKC modulators were studied in KB cell and KB/VCR.
方法:测定KB细胞及其耐药株的PKC活性及PKC调节剂对细胞药敏、药物代谢和耐药膜糖蛋白表达及其磷酸化的影响。
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