Instead the cells underwent cell cycle arrest with features of senescence.
代之以衰老为特征的细胞周期阻滞的表现。
Conclusion: chalcone can inhibit the growth of BGC823 and arrest the cell cycle.
结论:查尔酮可以抑制BGC823细胞生长,并呈剂量-反应关系。
Once the TP53 protein is activated, it can trigger the expression of several genes that influence cell cycle arrest and DNA repair or lead to apoptosis when DNA repair is failed.
一旦TP53蛋白被激活就能引发数种基因的表达来影响细胞周期阻滞、DNA修复、或者在DNA修复失败后引导凋亡发生。
Conclusions: Transfecting the exogenous FHIT gene into gastric cancer cells can suppress the proliferation of tumor cells, and can also induce apoptosis and cell cycle arrest.
结论:向胃癌细胞中导入外源性FHIT基因可以抑制肿瘤细胞增殖,诱导细胞凋亡并引起细胞生长周期阻滞。
Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis (1). P53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro (2, 3).
p53的激活能够引起细胞周期捕获和DNA修复或细胞凋亡(1)。离体或者在体情况下,p 53可以在多个位点被几个蛋白激酶进行磷酸化(2,3)。
Researchers believe that the combination therapy may activate an enzyme that controls cancer cell proliferation and induce cell cycle arrest ultimately causing the interruption of cancer growth.
研究人员相信这种联合疗法能够激活抑制癌细胞生长的酶,诱导最终抑制癌细胞生长的细胞周期停滞。
Conclusions Sulfide can significantly reduce the proliferation of ECV304, change the cell cycle distribution and arrest cells in G2-M phase where apoptosis may be induced.
结论舒林酸的硫化代谢产物能够显著抑制血管内皮细胞的增殖活性,改变细胞的周期分布,使细胞阻滞于G 2期,并可能在此期诱导其凋亡。
We used human acute promyelocytic leukemia cell line HL-60 to study the anti-tumor mechanisms of lycorine in two aspects: apoptosis and cell cycle arrest.
我们以人急性早幼粒白血病细胞株HL-60作为实验对象进行石蒜碱抗白血病作用机制研究,在凋亡相关基因表达变化和细胞周期阻滞两方面展开探讨。
We used human acute promyelocytic leukemia cell line HL-60 to study the anti-tumor mechanisms of lycorine in two aspects: apoptosis and cell cycle arrest.
我们以人急性早幼粒白血病细胞株HL-60作为实验对象进行石蒜碱抗白血病作用机制研究,在凋亡相关基因表达变化和细胞周期阻滞两方面展开探讨。
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