The birth defect rate was highest among women who took Topamax in combination with the epilepsy drug valproate, which has been linked to birth defects in numerous studies and epilepsy databases.
在妥泰联用抗癫痫药丙戊酸盐的女性中出生缺陷发生率最高，后者已被许多研究结果和癫痫数据库认定与出生缺陷相关。
The children were born between 1997 and 2003 and were participants in the National Birth Defects Prevention Study, which drew data from 10 birth-defect surveillance systems in 10 states.
这些孩子在1997-2003年之间出生，并且参加了国家出生缺陷预防研究，这项研究从10个州的10个出生缺陷监测系统中提取数据。
The children were born between 1997 and 2003 and were participants in the National Birth Defects Prevention Study, which drew data from 10 birth-defect surveillance systems in 10 states.
这些孩子在1997-2003年之间出生，并且参加了国家出生缺陷预防研究，这项研究从10个州的10个出生缺陷监测系统中提取数据。
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