It has superior bioavailability and transports well across the blood brain barrier and into cells.
它具有优越的生物利用度和运输跨越血脑屏障进入细胞。
AIM: Flunarizine is a blocker for calcium overload of cells, which could pass blood brain barrier.
目的:氟桂利嗪是通过血脑屏障的细胞钙超载阻滞剂。
NP-SLE patients with local CNS involvements showed mainly the damage of blood brain barrier(BBB) .
相反,局限性CNS受损患者主要表现为血脑屏障(BBB)破坏。
OBJECTIVE:To observe the effects of analog of TRH YM14673 on blood brain barrier after brain damage.
目的:观察TRH类似物YM14673对脑损伤后血脑屏障的影响。
Objective: To research the protective effects of Naochuangning on blood brain barrier in closed cerebral trauma mice.
目的:研究脑创宁对闭合性脑外伤模型小鼠血脑屏障的保护作用。
Objective To explore the effect of thrombin (TB) on the blood brain barrier(BBB) permeability and its possible mechanism.
目的探讨凝血酶(TB)对血脑屏障通透性的影响及其可能机制。
Aim to synthesize acylated prodrug of tacrine hydrochloride (THA) to improve the infiltration ability across the blood brain barrier (BBB).
目的制备盐酸他克林(THA)的酰化前体药物以提高其透过血脑屏障(BBB)的能力。
Conclusion: GAP-43 and ET-1 play important roles in the pathophysiological process of blood brain barrier damage after diffuse brain lesion.
结论GAP - 43及ET - 1在脑损伤后血脑屏障损害的病理生理过程中起重要作用。
Result:Naochuangning could obviously lessen the level of cerebral edema and cut down the content of Evans blue and protect the blood brain barrier.
结果:脑创宁可明显减轻模型小鼠脑水肿程度,降低伊文思蓝含量,保护血脑屏障。
Conclusion It is suggested that noradrenalin may enhance the permeability of blood brain barrier and trigger the aggravation of high altitude cerebral edema.
结论在高原状态下去甲肾上腺素可使血脑屏障通透性显著增高,诱发高原脑水肿加重。
Water soluble antihypoxic or hypoxia-resistant elements might exist in the brain of hypoxia resistant animals, which were extractable, transferable, and permeable to the blood brain barrier.
急性重复缺氧小鼠脑中的一种或多种可提取并可通过血脑屏障的水溶性物质可能为该适应变化的一部分。
Results (1) Permeability of blood brain barrier was increased in burn and burn with NE stimulating rats, with significantly statistical difference compared with normal control group (P<0.01).
结果(1)烧伤大鼠和NE刺激后的烧伤大鼠血脑屏障通透性增加,与对照组比较差异有统计学意义(P<0.01)。
Terbutaline crosses the placental barrier and blood-brain barrier of the fetus, which may lead to an autistic-spectrum disorder and other developmental disorders.
特布他林穿过胎盘屏障和胎儿的血脑屏障,可能导致自闭症系列障碍和其他精神障碍。
This is mainly because it is a large molecule, and has difficulty passing through the blood-brain barrier which protects the brain from potentially harmful compounds in the blood.
这主要是因为它是一种大分子物质,要穿过保护大脑免受血液中可能有害化合物入侵的血脑屏障很困难。
Treatment success in the second stage depends on a drug that can cross the blood-brain barrier to reach the parasite.
第二阶段的成功治疗依赖于可穿过血脑屏障达到寄生虫的一种药物。
Like the blood-brain barrier, this is only selectively permeable, keeping any toxins in the blood from reaching the delicate photoreceptors.
和血脑屏障相同,它是选择性可透的,阻挡血液中的有害物质进入到精致的感光层。
In the second stage the parasites cross the blood-brain barrier to infect the central nervous system.
在第二阶段,寄生虫穿过血脑屏障感染中枢神经系统。
It's the first time new 'biological' medicines have been delivered effectively across the blood-brain-barrier to the brain.
这是第一次有新的生物药剂能有效的通过血脑屏障,进入大脑。
We’ve shown that a natural system could be exploited to deliver drugs across the blood-brain barrier.
我们用自然分类系统可发出了跨过血脑屏障的药物技术。
'We've shown that a natural system could be exploited to deliver drugs across the blood-brain barrier.
我们用自然分类系统可发出了跨过血脑屏障的药物技术。
This would mean that a condition that affects the brain could be treated with something that does not cross the blood-brain barrier and does not come into contact with the brain.
这将意味着,大脑疾病的治疗可以无需穿过血脑屏障,也无需与大脑接触。
Dr Renslo and his colleagues have therefore been analysing and modifying the chemical structure of aminothiazoles to see if this can enable them to cross the blood-brain barrier.
为此,Renslo博士与其同事已经在分析并尝试修饰氨噻唑的分子结构,以使之能通过血脑屏障。
Now the Ioannou lab is studying whether this signal can also be transmitted across the blood-brain barrier to the lysosomes in brain cells to tell them to empty their stored waste products.
现在loannou实验室正在研究这种现象能够透过血脑屏障使脑细胞中的溶酶体释放溶菌酶去清除生理废物。
Tryptophan has to fight with other amino acids to cross the blood-brain barrier and get into the brain.
色氨酸必须打败其他的氨基酸,才能通过血管-大脑的障碍物,到达大脑。
The researchers used plasma because blood cells are actually too large to travel through the blood-brain barrier into the brain.
而之所以研究人员在实验中使用血浆,是因为血细胞较大,无法通过血脑壁障进入大脑。
The blood-brain barrier - which stops most things in the blood stream from crossing to our brains - is much too great an obstacle.
血脑障壁更是重大障碍,它有着阻止血液中许多物质进入我们大脑的作用。
Finding a drug that can cross the blood-brain barrier is the bane of drug development for Alzheimer's disease and other neurological disorders of the brain.
发现一种可以穿越血脑屏障的药物是阿尔茨海默氏病和其他脑部神经疾病药物研制中的障碍。
That made the aminothiazoles look more like cholesterol—which despite its malign everyday reputation is an important component of brains and routinely crosses the blood-brain barrier.
尽管胆固醇整天被认为是个对人体有害的物质,但它却是脑的重要成分,是通过血脑屏障的常客。
That made the aminothiazoles look more like cholesterol—which despite its malign everyday reputation is an important component of brains and routinely crosses the blood-brain barrier.
尽管胆固醇整天被认为是个对人体有害的物质,但它却是脑的重要成分,是通过血脑屏障的常客。
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