Karsenty's team further found that the bone resorption process creates an acidic environment that converts osteocalcin into an "active" form, which can escape bone and enter circulation.
卡尔·桑迪的研究小组进一步发现骨吸收过程创造出了一种酸性环境从而将骨钙蛋白转变为一种“积极”体,这种“积极”体能够脱离骨骼而进入血液循环。
Drugs that inhibit bone resorption [which are commonly used to treat osteoporosis] may, in certain patients, favor glucose intolerance, "Karsenty says."
而用于抑制骨吸收的各种药物(这些药物通常被用于治疗骨质疏松)有可能在一些特定的病人身上提升糖耐量。
Therefore, insulin's effects on the bones favors bone resorption.
因此可以说,胰岛素对骨骼的影响促进了骨吸收的进程。
And defects in the coupling of bone resorption and bone formation are accordant with the pathological process of modern medical diseases.
骨吸收与骨形成的偶联出现缺陷等,与现代医学疾病的病理过程相一致。
Periodontitis is an infectious diseases and the key feature is bone resorption, but the exact mechanism of etiology is unclear.
牙周炎是一类以牙槽骨吸收为主要特征的感染性疾病,但其病因理论中的许多具体机制尚未明了。
The bone resorption pits on bone slices were stained by toluidine blue and the resorption areas analyzed by computer image analysis software.
对骨片上形成的骨吸收陷窝进行甲苯胺蓝染色观察,并用计算机图像分析软件评估吸收面积的大小。
During bone resorption, the inorganic components of the bone matrix were first dissolved and resorbed leaving behind rough and irregular collagen fibrils.
骨吸收过程中,无机盐可以先吸收,残剩粗糙不规则的胶原纤丝。
Objective To study the change of bone formation markers and bone resorption markers in women of different ages.
目的探讨骨吸收与形成指标在不同年龄组妇女中的变化趋势。
Results: bone resorption was more obvious in alveolar bone with residual roots than that without roots.
结果:无牙根保留的牙槽骨吸收较有牙根保留的牙槽骨吸收明显。
Calcitonin inhibits the bone resorption, increases the bone mass and improves the abnormal bone structure. Calcitonin may prevent the bone loss in castrated male rats.
降钙素可抑制骨吸收,增加骨量,改善骨结构的异常,可预防去势大鼠骨质的丢失。
RESULTS:Osteoblasts and osteoclasts changed with different features in the elderly population, although their influences on bone formation and bone resorption were declined gradually.
结果:高龄人群成骨细胞骨形成作用和破骨细胞骨吸收作用对骨骼的影响都逐渐下降,但表现出不同的特点。
Our studies also established that insulin signaling in osteoblasts was a positive regulator not only of postnatal bone acquisition but also of bone resorption.
我们的研究还证实,成骨细胞中的胰岛素信号是一个积极的信号调节,不仅对于出生后骨获得而且也包括骨吸收。
CONCLUSION: RLX reduces bone turnover rate of the healthy Chinese postmenopausal women, inhibits bone resorption and prevents osteoporosis.
结论:盐酸雷洛昔芬可降低健康的中国绝经后妇女骨转换率,抑制骨吸收,可预防骨质疏松。
Summary of Background Data. Osteopetrosis is characterized by osteoclast dysfunction, impaired bone resorption, and poor bone remodeling.
石骨症的特征是破骨细胞功能出现障碍,使骨吸收减慢,导致骨再建缺陷。
All groups had alveolar bone resorption.
各组均有牙槽骨吸收。
Alveolar bone resorption is the major reason of dysmasesia and dyspepsia.
牙槽骨吸收是导致临床咀嚼困难和失牙的主要原因。
It appears that these factors are unique BRF, which are different from other known factors that can cause bone resorption.
实验结果表明此溶骨因子不同于其它已知能引起溶骨的因子。
Results There was close relationship between the development of skeletal fluorosis and bone formation related gene and bone resorption related gene.
结果骨形成相关基因和骨吸收相关基因与氟骨症的发生密切相关。
The transient activation of bone resorption function, presented as the temporary increase of osteoclasts number and mostly maintenance of its function of excreting acid and protease.
骨吸收功能短暂激活,主要表现为:破骨细胞数量一度增加,而其泌酸和蛋白酶功能基本得以保持。
SOS was also negatively related to bone resorption markers.
骨超声声速与骨吸收指标呈负相关。
The creeping substitution of the devitalized bone was mainly manifested by bone resorption within 12 weeks postoperatively.
术后12周以前,灭活骨段的爬行替代以骨吸收表现为主。
The relationship between histomorphometric parameters of bone resorption and serum TRACP was evaluated in 14 chronically dialyzed patients and 6 healthy control subjects.
评估14 个慢性地肾透析患者和6个健康的人作为临控,研究骨重吸收的组织形态学参数与血清TRACP之间的相关性。
By now, a large number of studies have demonstrated that many cytokines have important influences on the remodeling of the alveolar bone, including bone resorption and bone regeneration.
目前,大量国内外研究证明,许多细胞因子也对牙槽骨的重建有重要影响,在骨吸收和骨再生方面有不同的刺激作用。
The bone formation process, however, is entirely different from the bone resorption process in arthritis.
骨形成过程完全不同于关节炎中的骨吸收。
Conclusions Alendronate can effectively prevent bone loss to reduce osteoporosis in ovariectomized rats and prohibit pathological alveolar bone resorption.
结论阿仑膦酸钠能减少骨质丢失从而可以防止骨质疏松及病理性牙槽骨骨吸收。
Conclusions Osteoclast-mediated bone resorption was inhibited by the bisphosphonate administration.
结论双膦酸盐对破骨细胞性骨吸收有明显的抑制作用。
ConclusionThe cancellous bone density of OVX rats can be evidently improved by increasing bone formation and inhibiting the endocortical bone resorption.
结论强骨宝对去卵巢大鼠骨质疏松症的作用,从骨形态计量参数变化上看能促进骨形成,抑制骨吸收,增加松质骨的密度;
The results showed that the position and degrees of bone resorption had close relation to the position of denture bite.
结果表明骨吸收部位和程度与义齿咬合面的负荷位置关系密切。
Conclusion: Nylestriol can inhibit expression of IL 6 mRNA, reduce osteoclastic bone resorption and decrease loss of bone mass.
结论:尼尔雌醇可以抑制IL6基因表达,从而抑制破骨细胞骨吸收,减少骨量丢失。
Conclusion: Nylestriol can inhibit expression of IL 6 mRNA, reduce osteoclastic bone resorption and decrease loss of bone mass.
结论:尼尔雌醇可以抑制IL6基因表达,从而抑制破骨细胞骨吸收,减少骨量丢失。
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