Mutations of the human breast cancer susceptibility gene 1 (BRCA1) confers a risk for breast, ovarian and prostate cancers and BRCA1 exerts multiple biological functions.
人类乳癌易感基因1 (BRCA1)是乳癌，卵巢癌和前列腺癌的危险因素之一，而且表现出许多的生物功能。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of DNA damage response and DNA repair.
乳腺癌易感基因，BRCA1，编码一种E3泛素连接酶，BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of the DNA damage response and DNA repair.
乳腺癌易感基因，BRCA1，编码一种E3泛素连接酶，BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
This gene is different from the breast-cancer susceptibility genes, BRCA1 and BRCA2, which women are born with.
这些基因不同于以往的乳腺癌易感基因BRCA1和BRCA2。以往的易感基因是先天具有的。
This review will address the research advancement in genetic studies of breast cancer susceptibility as well as the screening methods for gene mutations.
现就近年来乳腺癌易感基因的遗传学研究及基因变异的筛查技术进展作一综述。
This review will address the research advancement in genetic studies of breast cancer susceptibility as well as the screening methods for gene mutations.
现就近年来乳腺癌易感基因的遗传学研究及基因变异的筛查技术进展作一综述。
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