• Calcineurin inhibitors (CNIs) are the cornerstone of immunosuppression after liver transplantation.

    钙调磷酸酶抑制剂(CNIs)移植术后免疫抑制基石

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  • In all, 12 patients were neutropenic (<500/microl) at baseline, 10 received steroids and 16 calcineurin inhibitors or sirolimus.

    共12基线时有粒细胞缺乏(<500/微升),10接受类固醇激素治疗16例接受了钙调磷酸酶抑制剂西罗莫斯治疗

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  • Calcineurin B-like (CBL) proteins are calcium-binding proteins that are thought to function as plant signal transduction elements.

    类钙调神经磷酸酶B亚基(CBL蛋白一种结合蛋白,认为植物信号传导中发挥功能

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  • CONCLUSION: Ectogenesis Ald can negatively control the generation and secretion of NPY, through calcineurin depended signal-pathway.

    结论外源性醛固酮可通过激活钙调神经磷酸酶信号通路,调控神经肽y的生成分泌

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  • Results Benazepril reduced left ventricular weight, decreased blood pressure, reduced hyperplasia of collagen and calcineurin activation, and make microstructure stable as well.

    结果苯那普利可以减轻心室重量降低血压减少胶原增生使心肌中调神经磷酸酶活性降低,微结构稳定

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  • If you look at the vast majority of the data and the meta-analyses that have been done, it really shows no difference in HCV recurrence rates between both calcineurin inhibitors.

    如果查阅多数数据完成综合分析,会发现两种神经素抑制剂对HCV复发率影响,实际上没有差异

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  • This article reviews published experience to date with steroid and calcineurin minimization in pediatric renal transplantation and discusses the risks and benefits of these approaches.

    篇文章综述了迄今为止已发表儿童移植应用类固醇钙调磷酸酶最小化经验讨论了这些治疗方法的风险益处

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  • Conclusions - Our study identifies a novel cardiac apoptotic pathway in which ARC is dephosphorylated by calcineurin. This pathway could be a component in the cardiac apoptotic machinery.

    结论我们研究发现了一条新的心脏凋亡通路其中神经素使ARC发生去磷酸化反应诱导凋亡的发生。条通路可能成为心脏凋亡机制中的组成部分

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  • Conclusions - Our study identifies a novel cardiac apoptotic pathway in which ARC is dephosphorylated by calcineurin. This pathway could be a component in the cardiac apoptotic machinery.

    结论我们研究发现了一条新的心脏凋亡通路其中神经素使ARC发生去磷酸化反应诱导凋亡的发生。条通路可能成为心脏凋亡机制中的组成部分

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